General Issue ARKIVOC 2011 (i) 111-195
Recent advances on the synthesis of azoles, azines and azepines
fused to benzimidazole
Kamal M. Dawood,
a,
* Nehal M. Elwan,
a
and Bakr F. Abdel-Wahab
b
a
Department of Chemistry, Faculty of Science, University of Cairo, Giza, Egypt
b
Department of Chemistry, Faculty of Science and Arts, King Abdulaziz University, Khulais
Branch, Saudi Arabia
E-mail: dr_dawood@yahoo.com
Abstract
The current review article represents a survey covering the literatures on azoles, azines and
azepines fused to the a face of a benzimidazole moiety since 1980. Synthetic routes leading to
benzimidazole fused with different ring systems; five-, six-, and seven-membered heterocyclic
rings, containing one-, two- and three-heteroatoms were reported utilizing simple reactive
benzimidazole synthons
Keywords: Benzimidazoles, triheterocycles, synthesis, azoles, azines, azepines
Contents
1. Introduction
2. Synthesis of Azolo-fused-benzimidazoles
2.1. Pyrrolobenzimidazoles
2.2. Pyrazolobenzimidazoles
2.3. Imidazobenzimidazoles
2.4. Oxazolobenzimidazoles
2.5. Thiazolobenzimidazoles
2.6. Triazolobenzimidazoles
2.7. Thiadiazolobenzimidazoles
2.8. Oxadiazolobenzimidazoles
3. Synthesis of Azino-fused-benzimidazoles
3.1. Pyridobenzimidazoles
3.2. Pyrimidobenzimidazoles
3.3. Pyrazinobenzimidazoles
3.4. Triazinobenzimidazoles
3.5. Thiazinobenzimidazoles
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