ABSTRACT Angiomyomatous hamartoma is a rare tumour of lymph nodes. This report describes a case of angiomyomatous hamartoma in the inguinal lymph node. The patient was a 33-year-old woman who underwent surgery because of a right inguinal mass. The excised specimen consisted of a grossly enlarged lymph node covered with fatty tis- sue, measuring 4.5 cm in diameter. On microscopic exa- mination, the lymph node parenchyma was replaced by haphazardly dispersed thick-walled vessels and smooth muscle cells in a fibrous background. This process ex- tended to the cortex from the hilum, and there was a thin cortical lymphoid tissue. Immunohistochemical ac- tin staining indicated smooth muscle cells dispersing in- to the fibrous background. Although angiomyomatous hamartoma of lymph nodes is very rare, its recognition is important for differential diagnosis from angiomato- us malignant tumors of lymph nodes. Key words: Angiomyomatous hamartoma, inguinal, lymph node ÖZET Anjiomyomatöz hamartom lenf dü¤ümlerinin nadir gö- rülen bir tümörüdür. Bu çal›flmada, inguinal lenf dü¤ü- münde anjiomyomatöz hamartom saptanan bir olgu su- nulmaktad›r. Otuz üç yafl›nda kad›n hastada eksizyonel biyopsi ile al›nan sa¤ inguinal kitlenin, makroskopik olarak 4.5 cm çap›nda, ya¤ dokusu ile kapl› bir lenf dü- ¤ümü oldu¤u saptand›. Mikroskopik incelemede, fibröz zeminde gelifligüzel yerleflmifl kal›n duvarl› vasküler ya- p›lar ve arada da¤›lm›fl düz kas hücrelerinin lenf dü¤ü- mü parankiminin yerini alarak hilustan kortekse do¤ru uzand›¤› izlendi. Kortekste ince bir kortikal lenfoid do- ku mevcuttu. Zeminde da¤›lm›fl düz kas hücreleri yap›- lan immünhistokimyasal çal›flmada aktin ile pozitif bo- yand›. Lenf dü¤ümlerinin anjiomiyomatöz hamartomu çok nadir görülmekle birlikte, lenf nodlar›n›n anjioma- töz malign tümörlerinin ay›r›c› tan›s›nda önemlidir. Anahtar sözcükler: Anjiomyomatöz hamartom, ingui- nal, lenf dü¤ümü INTRODUCTION Primary vascular tumors other than Kaposi sarcoma are rare in lymph nodes (1). Angiomyo- matous hamartoma is a benign vascular disease of lymph nodes with unknown etiology. This ra- re disease particularly involves inguinal lymph nodes. Few cases of femoral or cervical lymph node involvement have been reported (1-6). We report here a case of angiomyomatous hamartoma in the inguinal lymph node in a 33- year-old woman. CASE REPORT A 33-year-old woman complaining of swelling that had persisted for 10 years in her right inguinal region was admitted in our clinics. On examination, a hard, mobile mass with a di- ameter of 3 cm was found in the right inguinal region, and the mass was excised with a clinical diagnosis of soft tissue tumor. Gross examinati- on of the excised material demonstrated a mass Angiomyomatous hamartoma in the inguinal lymph node: A case report ‹nguinal lenf dü¤ümünde anjiyomatöz hamartom: Olgu sunumu Yurdanur SÜLLÜ 1 , Seda GÜN 1 , Nevzat DABAK 2 , Filiz KARAGÖZ 1 Department of Pathology 1 and Department of Orthopedics 2 , Ondokuz Mayis University, Faculty of Medicine This study was presented as a poster presentation in the XXIII. World Congress of Pathology and Laboratory Medicine Meeting (May 26-30, 2005, Istanbul). Corresponding Author: Dr. Yurdanur Sullu, Department of Pathology Ondokuz Mayis University Faculty of Medicine, 55139, Samsun, Turkey 42 Turkish Journal of Pathology 2006;22(1):42-44