Cite this article as: Brunswicker A, Taylor M, Grant SW, Abah U, Smith M, Shackcloth M et al. Pneumonectomy for primary lung cancer: contemporary outcomes, risk factors and model validation. Interact CardioVasc Thorac Surg 2021; doi:10.1093/icvts/ivab340. Pneumonectomy for primary lung cancer: contemporary outcomes, risk factors and model validation Annemarie Brunswicker a, ‡ , Marcus Taylor a, * , ‡ , Stuart W. Grant b , Udo Abah c , Matthew Smith c , Michael Shackcloth c , Felice Granato a , Rajesh Shah a and Kandadai Rammohan a ; on behalf of the North West Thoracic Surgery Collaborative (NWTSC)† a Department of Cardiothoracic Surgery, Manchester University Hospital NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK b Division of Cardiovascular Sciences, University of Manchester, ERC, Manchester University Hospital NHS Foundation Trust, Manchester, UK c Department of Cardiothoracic Surgery, Liverpool Heart & Chest Hospital, Liverpool, UK * Corresponding author. Department of Cardiothoracic Surgery, Manchester University NHS Foundation Trust, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK. Tel: +44-7910538817; e-mail: marcus.taylor1@nhs.net (M. Taylor). Received 24 April 2021; received in revised form 27 July 2021; accepted 7 November 2021 Abstract OBJECTIVES: Despite the increased rate of adverse outcomes compared to lobectomy, for selected patients with lung cancer, pneumo- nectomy is considered the optimal treatment option. The objective of this study was to identify risk factors for mortality in patients under- going pneumonectomy for primary lung cancer. † The members of the North West Thoracic Surgery Collaborative (NWTSC) are listed in the Acknowledgements section. ‡ Annemarie Brunswicker and Marcus Taylor are joint first authors with equal contribution. THORACIC V C The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which per- mits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Interactive CardioVascular and Thoracic Surgery (2021) 1–8 ORIGINAL ARTICLE https://doi.org/10.1093/icvts/ivab340 Downloaded from https://academic.oup.com/icvts/advance-article/doi/10.1093/icvts/ivab340/6453861 by guest on 07 December 2021