This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/cge.13625 Title: Whole exome and targeted gene sequencing to detect pathogenic recessive variants in early onset cerebellar ataxia Sunil Shakya 1$,PhD , Renu Kumari 2,5,$,MSc , Varun Suroliya 1,MSc , Nishu Tyagi 2,MSc , Aditi Joshi 2,MSc , Ajay Garg 3,MD , Inder Singh 1,PhD , Divya K P 4,DM , Ajith Cherian 4,DM , Mitali Mukerji 2,5,PhD , Achal K. Srivastava 1,DM* , Mohammed Faruq 2,5,MBBS, PhD* 1 Department of Neurology, Neuroscience Centre, All India Institute of Medical Sciences, New Delhi, India, 110029 2 Genomics and Molecular Medicine, CSIR-Institute of Genomics and Integrative Biology (CSIR -IGIB), Mall Road, Delhi 110007 India 3 Neuroradiology Department, Neuroscience Centre, All India Institute of Medical Sciences, New Delhi, 110029, India 4 Department of Neurology, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Trivandrum, India 5 Academy of Scientific and Innovative Research, CSIR-IGIB South Campus, Mathura Road, Delhi 110025, India $ Equal contribution *Co-corresponding author Corresponding author Mohammed Faruq, MBBS, PhD Genomics and Molecular Medicine, CSIR-Institute of Genomics and Integrative Biology (CSIR -IGIB), Mall Road, Delhi 110007 Tel: 91-9910953040, Fax: +91-11-27667471 Email ID: faruq.mohd@igib.res.in This article is protected by copyright. All rights reserved.