Performance of Avian Influenza Surveillance System, Ogun State Nigeria, 2015-2019 Abstract- Background: In 2019, two Highly pathogenic avian influenza (HPAI) A(H5N8) outbreaks in poultry establishments in Bulgaria, two of wild birds in Denmark and one low pathogenic avian influenza (LPAI) A(H5N3) in captive birds in the Netherlands were reported. Nigeria recorded the first outbreak of Highly Pathogenic Avian Influenza (HPAI) in February 2006 in a commercial poultry farm. Nigerian Pandemic Preparedness and Action Plan for Avian Influenza were then used to respond.Although influenza sentinel surveillance has been established in several African countries including Nigeria, data about the performance of established surveillance systems are limited on the continent.We described the avian influenza (AI) surveillance system in Ogun State, accessed veterinary health workers and farmers knowledge, evaluated all its attributes and made recommendations to improve the AI surveillance system. Methods: We adopted 2001 CDC Updated Guidelines for Evaluating Public Health Surveillance Systems. We reviewed and analyzed passive surveillance data from Ogun State Ministry of Agric, key informant interviews were conducted for relevant stakeholders at the state level and Local Government divisional veterinary clinics and farms to obtain additional information on the operations of the system. Keywords: avian influenza, surveillance, evaluation, ogun-state. GJMR-G Classification: NLMC Code: WA 105 PerformanceofAvianInfluenzaSurveillanceSystemOgunStateNigeria20152019 Strictly as per the compliance and regulations of: Global Journal of Medical Research: G Veterinary Science and Veterinary Medicine Volume 20 Issue 1 Version 1.0 Year 2020 Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Online ISSN: 2249-4618 & Print ISSN: 0975-5888 By Folajimi. O. Shorunke, Aisha Usman, Tade Adeniyi Olanrewaju, Ndadilnasiya Endie Waziri & Kia Grace S.N © 2020. Folajimi. O. Shorunke, Aisha Usman, Tade Adeniyi Olanrewaju, Ndadilnasiya Endie Waziri & Kia Grace S.N. This is a research/review paper, distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.