Journal Pre-proof Distinct response of immune gene expression in peripheral blood leucocytes modulated by bacterin vaccine candidates in rainbow trout Oncorhynchus mykiss: A potential in vitro screening and batch testing system for vaccine development in aquaculture Ahmed Attaya, Yousheng Jiang, Christopher J. Secombes, Tiehui Wang PII: S1050-4648(19)30795-8 DOI: https://doi.org/10.1016/j.fsi.2019.08.002 Reference: YFSIM 6343 To appear in: Fish and Shellfish Immunology Received Date: 4 April 2019 Revised Date: 2 July 2019 Accepted Date: 1 August 2019 Please cite this article as: Attaya A, Jiang Y, Secombes CJ, Wang T, Distinct response of immune gene expression in peripheral blood leucocytes modulated by bacterin vaccine candidates in rainbow trout Oncorhynchus mykiss: A potential in vitro screening and batch testing system for vaccine development in aquaculture, Fish and Shellfish Immunology (2019), doi: https://doi.org/10.1016/j.fsi.2019.08.002. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier Ltd.