Med Intensiva. 2016;40(9):541---549 www.elsevier.es/medintensiva ORIGINAL Comparative analysis between 2 periods of acute myocardial infarction after a decade in Mallorca. IBERIA Study (1996---1998) and Infarction-Code (2008---2010) L. Socias a,* , G. Frontera b , C. Rubert a , A. Carrillo c , V. Peral d , A. Rodriguez c , C. Royo c , M. Ferreruela c , J. Torres e , R. Elosua f , A. Bethencourt d , M. Fiol b , on behalf of the CI-IB and IBERICA Research Group a Servicio de Medicina Intensiva, Hospital Son Llàtzer, Palma de Mallorca, Spain b Instituto de Investigación Sanitaria de Palma (IdISPa), Hospital Universitario Son Espases, Palma de Mallorca, Spain c Servicio de Medicina Intensiva, Hospital Universitario Son Espases, Palma de Mallorca, Spain d Servicio de Cardiología, Hospital Universitario Son Espases, Palma de Mallorca, Spain e Servicio de Cardiología, Hospital Son Llàtzer, Palma de Mallorca, Spain f IMIM-Institut Hospital del Mar d’Investigacions Mèdiques, Barcelona, Spain Received 10 January 2016; accepted 18 April 2016 KEYWORDS Acute coronary syndrome with ST elevation; Acute myocardial infarction; Infarction Code; Care program; Mortality Abstract Objective: To investigate the differences in mortality at 28 days and other prognostic variables in 2 periods: IBERICA-Mallorca (1996---1998) and Infarction Code of the Balearic Islands (IC-IB) (2008---2010). Design: Two observational prospective cohorts. Setting: Hospital Universitario Son Dureta, 1996---1998 and 2008---2010. Patients: Acute coronary syndrome with ST elevation of 24 h of anterior and inferior site. Main variables of interest: Age, sex, cardiovascular risk factors, site of AMI, time delays, reper- fusion therapy with fibrinolysis and primary angioplasty, administration of acetylsalicylic acid, beta blockers and angiotensin converting enzyme inhibitors. Killip class, malignant arrhythmias, mechanical complications and death at 28 days were included. Please cite this article as: Socias L, Frontera G, Rubert C, Carrillo A, Peral V, Rodriguez A, et al. Análisis comparativo de 2 registros de infarto agudo de miocardio tras una década de cambios. Estudio IBERICA (1996---1998) y Código Infarto-Illes Balears (2008---2010). Med Intensiva.2016;40:541---549. * Corresponding author. E-mail address: lsocias@hsll.es (L. Socias). The names of the members of the CI-IB and IBERICA Research Group are listed in Annex I. 2173-5727/© 2016 Published by Elsevier Espa˜ na, S.L.U.