Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/all.13313 This article is protected by copyright. All rights reserved. DR. HARISSIOS VLIAGOFTIS (Orcid ID : 0000-0002-5029-855X) Article type : Original Article: Experimental Allergy and Immunology Handling AE: Angela Haczku Protease-Activated Receptor-2 blockade inhibits changes seen in a chronic murine asthma model Muhammad Asaduzzaman 1 , Courtney Davidson 1 , Drew Nahirney 1 , Yahya Fiteih 1 , Lakshmi Puttagunta 2 , and Harissios Vliagoftis 1 1 Pulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, AB Canada; 2 Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB Canada Sources of funding: This work was supported by grants from the Canadian Institutes of Health Research, Alberta Innovates-Health Solutions and the Lung Association of Alberta and Northwest Territories. Corresponding author Harissios Vliagoftis Department of Medicine University of Alberta 550A Heritage Medical Research Center Edmonton, Alberta, T6G 2S2, Canada Phone: +1-780-492-9295