Natarajan Meghanathan et al. (Eds) : ICAIT, CRYPIS, NC, ITCSE-2016 pp. 01–11, 2016. © CS & IT-CSCP 2016 DOI : 10.5121/csit.2016.60701            Doris Cáliz1, Loïc Martínez 1 , Xavier Alamán 2 , Carlos Terán 3 , Richart Cáliz 3 . 1 Department ETSIINF, DLSIIS, Madrid Polytechnic University, Campus de Montegancedo 28660 , Boadilla del Monte , Madrid, Spain doriscalizramos@outlook.com; loic@fi.upm.es; 2 Department of Computer Engineering, Autonomous University, Madrid, C/ Francisco Tomás y Valiente, 11. 28049, Madrid, Spain. Xavier.Alaman@uam.es 3 Department of Computer Sciences FIS Group, National Polytechnic University, Ladrón de Guevara E11-25 y Andalucía Quito, Ecuador carlos.teran@cobiscorp.com; richartharold@hotmail.com ABSTRACT We present a review of research related to the usability testing of mobile applications including participants with Down syndrome. The purpose is to identify good usability testing practices and possible guidelines for this process when participants are people with this cognitive disability. These practices and guidelines should account for their specific impairments. We applied document analysis techniques to searches of scientific databases. The results were filtered considering how well they matched the research topic. We processed and reported the classified and summarized results. The main findings of this literature review is that mobile applications usability testing including people with Down syndrome is an issue that has not be comprehensively investigated. While there is some related research, this is incomplete, and there is no single proposal that takes on board all the issues that could be taken into account. Consequently, we propose to develop guidelines on the usability testing process involving participants with Down syndrome. KEYWORDS Usability Testing, Mobile Applications, Cognitive Disability, Down Syndrome, Human Computer Interaction (HCI), Mobile Devices. 1. INTRODUCTION Usability is a quality attribute of interactive systems defined by five attributes: learnability, efficiency, memorability, errors and satisfaction (Nielsen and Kaufmann). In ISO 9241-11