S1 Electronic Supporting Information Copper-catalyzed oxidative cleavage of Passerini and Ugi adducts in basic medium yielding α-ketoamides Anirban Ghoshal, a,b,c Mayur D. Ambule, a,b Revoju Sravanthi, c Mohit Taneja c and Ajay Kumar Srivastava* ,a,b a Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow- 226031, UP, India b Chemical Sciences Division, Academy of Scientific and Innovative Research (AcSIR), New Delhi- 110025, India c Organic Synthesis and Process Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India Table of Contents 1. Optimization studies for oxidative cleavage of Ugi adducts S2 2. Labeling experiments S3-S8 3. Kinetic Isotope Effect (KIE) measurement by independent reactions S9-S10 4. References S10 5. Copies of 1 H and 13 C NMR spectra S11-S98 Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2019