Accepted Manuscript Xanthine-derived KMUP-1 reverses glucotoxicity-activated Kv channels through the cAMP/PKA signaling pathway in rat pancreatic β cells Chien-Hsing Lee, Chih-Sheng Chu, Han-Jie Tsai, Liang-Yin Ke, Hsiang-Chun Lee, Jwu-Lai Yeh, Chu-Huang Chen, Bin-Nan Wu PII: S0009-2797(17)30698-1 DOI: 10.1016/j.cbi.2017.11.017 Reference: CBI 8153 To appear in: Chemico-Biological Interactions Received Date: 28 June 2017 Accepted Date: 23 November 2017 Please cite this article as: C.-H. Lee, C.-S. Chu, H.-J. Tsai, L.-Y. Ke, H.-C. Lee, J.-L. Yeh, C.-H. Chen, B.-N. Wu, Xanthine-derived KMUP-1 reverses glucotoxicity-activated Kv channels through the cAMP/ PKA signaling pathway in rat pancreatic β cells, Chemico-Biological Interactions (2017), doi: 10.1016/ j.cbi.2017.11.017. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.