The Korean Journal of Applied Statistics (2017) 30(2), 301–309 DOI: https://doi.org/10.5351/KJAS.2017.30.2.301 A minimum combination t-test method for testing differences in population means based on a group of samples of size one Miyoung Heo a · Changwon Lim a, 1 a Department of Applied statistics, Chung-Ang University (Received February 24, 2017; Revised February 26, 2017; Accepted February 26, 2017) Abstract It is often possible to test for differences in population means when two or more samples are extracted from each N population. However, it is not possible to test for the mean difference if one sample is extracted from each population since a sample mean does not exist. But, by dividing a group of samples extracted one by one into two groups and generating a sample mean, we can identify a heterogeneity that may exist within the group by comparing the differences of the groups’ mean. Therefore, we propose a minimum combination t-test method that can test the mean difference by the number of combinations that can be divided into two groups. In this paper, we proposed a method to test differences between means to check heterogeneity in a group of extracted samples. We verified the performance of the method by simulation study and obtained the results through real data analysis. Keywords: heterogeneity, minimum combination t-test method, comparison of means, hypothesis testing 1. 1908William Sealy GossetStudent (1908)t- t-야에. 값과 같, . 3 t-. 1918Ronald A. Fisher음으(Fisher, 1918), 야에. t-전제조어야 추출2 어야 다는 . 추출 을위, 2 어야 . This research was supported by the Chung-Ang University Research Scholarship Grants in 2015. 1 Corresponding author: Department of Applied Statistics, Chung-Ang University, 84, Heukseok-ro, Dongjak-gu, Seoul 06974, Korea. E-mail: clim@cau.ac.kr