Ophthalmology and Vision Science Case Report V Swetha E Jeganathan 1,2 , Ala Noaman 3 and Andrew Blaikie 4,5 * 1 W.K. Kellogg Eye Center, Michigan Medicine, Ann Arbor, USA 2 Department of Biomedical Engineering, University of Michigan, Ann Arbor, USA 3 University of Edinburgh, Edinburgh, Scotland 4 Department of Ophthalmology, Queen Margaret Hospital, Dunfermline, Scotland 5 Global health Implementation, University of St Andrews School of Medicine, St Andrews, Scotland Received: September 14, 2017; Published: September 26, 2017 *Corresponding Author: Andrew Blaikie, Senior Lecturer, Global Health Implementation, University of St Andrews School of Medicine, St Andrews, Scotland. An Unusual Cause of Optic Atrophy in Childhood Abstract Purpose: To report a rare and interesting cause of bilateral optic atrophy secondary to hemolytic uremic syndrome (HUS). Case Report: A 6-year-old asymptomatic child was referred with bilateral pale optic discs. She was otherwise healthy, with no known family history of any eye problems. On detailed questioning, it was revealed that she had HUS secondary to E. coli diarrheal infec- tion at the age of 2.5 years, with renal failure that necessitated treatment with dialysis. Retinal nerve fiber analysis confirmed poor reserves with fewer axons in both eyes. The patient was followed up and discharged when there were no signs of progression. Conclusion: Ocular involvement in HUS although rare, depicts a severe form of HUS, and may develop as sequelae to ischemic or toxic insults. Ophthalmology referral is required especially in preverbal patients with HUS to exclude potential vision-endangering consequences. Volume 1 • Issue 3 • 2017 Page 125 to 128 Citation: Andrew Blaikie., et al. “An Unusual Cause of Optic Atrophy in Childhood”. Ophthalmology and Vision Science 1.3 (2017): 125- 128. Key words: Optic atrophy; Hemolytic uremic syndrome; Ophthalmology; Children; Dialysis ISSN: 2573-4997 Volume 1 Issue 3 September 2017 © All Copy Rights Reserved by Andrew Blaikie., et al. We present a very unusual cause of optic atrophy that was identified on detailed clinical history. A 6-year-old female patient was referred by the optometrist to our local Ophthalmology department with bilateral pale optic discs. The patient did not report any ophthalmological problems. She denied any headaches, photophobia, malaise or night blindness, and did Introduction Case Report Abbreviations: HUS: Hemolytic Uremic Syndrome; OCT: Optical Coherence Tomography;