Journal Pre-proof Assessment of a Clinical Trial Metric for Rett Syndrome: Critical Analysis of the Rett Syndrome Behavioural Questionnaire Wei Hou, PhD, Usree Bhattacharya, PhD, Wisnu A. Pradana, Daniel C. Tarquinio, DO MS-CI PII: S0887-8994(20)30035-7 DOI: https://doi.org/10.1016/j.pediatrneurol.2020.01.009 Reference: PNU 9716 To appear in: Pediatric Neurology Received Date: 2 December 2019 Accepted Date: 21 January 2020 Please cite this article as: Hou W, Bhattacharya U, Pradana WA, Tarquinio DC, Assessment of a Clinical Trial Metric for Rett Syndrome: Critical Analysis of the Rett Syndrome Behavioural Questionnaire, Pediatric Neurology (2020), doi: https://doi.org/10.1016/j.pediatrneurol.2020.01.009. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Elsevier Inc. All rights reserved.