Pediatric Transplantation. 2018;22:e13110. wileyonlinelibrary.com/journal/petr
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https://doi.org/10.1111/petr.13110
© 2018 John Wiley & Sons A/S.
Published by John Wiley & Sons Ltd
1 | INTRODUCTION
As a result of continued research and advancements in clinical prac-
tice, 5-year survival rates for pediatric heart transplant recipients
are approaching or exceeding 80%, depending on age at transplant.
1
Given that the purpose of transplantation is not only to extend life but
also to enhance the quality of life among this population,
2
attention
to outcomes other than survival is needed. With increasing longev-
ity of pediatric heart transplant recipients, it is important to evaluate
the emotional, behavioral, and social functioning of these patients and
their families throughout their post-transplant life. Furthermore, un-
derscoring its importance, recipient and parent psychosocial function-
ing is associated with health-related outcomes in pediatric solid organ
transplant populations, including adherence to the immunosuppres-
sant regimen
3,4
and number of hospitalizations.
5
Results of limited studies have suggested that while the majority
of pediatric heart transplant recipients report normative psycholog-
ical health, a subset of recipients are at increased risk for long-term
sequelae. Approximately 30% of pediatric heart transplant recipients
have been found to have clinically significant mental health problems
Accepted: 7 December 2017
DOI: 10.1111/petr.13110
ORIGINAL ARTICLE
Psychosocial functioning in pediatric heart transplant
recipients and their families
Melissa K. Cousino
1,2
| Kurt R. Schumacher
1,2
| Kelly E. Rea
1
| Sally Eder
1
| Mary
Zamberlan
3
| Jessica Jordan
1
| Emily M. Fredericks
1,2,4
Abbreviations: PAT, Psychosocial Assessment Tool; PPPHM, Pediatric Psychosocial
Preventative Health Model; SD, standard deviations.
1
Department of Pediatrics, Michigan
Medicine, Ann Arbor, MI, USA
2
University of Michigan Transplant Center,
Ann Arbor, MI, USA
3
Department of Cardiac Surgery, Michigan
Medicine, Ann Arbor, MI, USA
4
Child Health Evaluation and Research
Center, University of Michigan, Ann Arbor,
MI, USA
Correspondence
Melissa K. Cousino, Department of Pediatrics,
Michigan Medicine, Ann Arbor, MI, USA.
Email: melcousi@med.umich.edu
Funding information
University of Michigan Transplant Center
Abstract
Across pediatric organ transplant populations, patient and family psychosocial func-
tioning is associated with important health-related outcomes. Research has suggested
that pediatric heart transplant recipients and their families are at increased risk for
adverse psychosocial outcomes; however, recent investigation of psychosocial func-
tioning in this population is lacking. This study aimed to provide a contemporary char-
acterization of psychosocial functioning in pediatric heart transplant recipients and
their families. Associations between psychosocial function, demographic variables,
and transplant-related variables were investigated. Fifty-six parents/guardians of
pediatric heart transplant recipients completed a comprehensive psychosocial screen-
ing measure during transplant follow-up clinic visits. Descriptive statistics, correla-
tional analyses, and independent samples t tests were performed. Forty percent of
pediatric heart transplant recipients and their families endorsed clinically meaningful
levels of total psychosocial risk. One-third of patients presented with clinically signifi-
cant psychological problems per parent report. Psychosocial risk was unassociated
with demographic or transplant-related factors. Despite notable improvements in the
survival of pediatric heart transplant recipients over the past decade, patients and
families present with sustained psychosocial risks well beyond the immediate post-
transplant period, necessitating mental health intervention to mitigate adverse impact
on health-related outcomes.
KEYWORDS
heart transplant, pediatric transplant, psychosocial functioning, psychosocial screening