Journal français d’ophtalmologie (2019) 42, 586—591
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ORIGINAL ARTICLE
Evaluation of lamina cribrosa in angioid
streaks using spectral-domain optical
coherence tomography enhanced depth
imaging
Evaluation par tomographie en cohérence optique en domaine spectral à
l’imagerie à profondeur améliorée de la lame criblée chez des patients
atteints des stries angioïdes
G. Demir
*
, C. Altan , S. Cakmak , H. Topcu, D. Yasa,
A. Demircan , Z. Alkin
University of Health Sciences, Beyoglu Eye Training and Research Hospital, Bereketzade Cami
Sok. No 2 Beyoglu, Istanbul, Turkey
Received 26 October 2018; accepted 17 December 2018
Available online 14 May 2019
KEYWORDS
Angioid streaks;
Retinal nerve fiber
layer thickness;
Anterior lamina
cribrosa depth;
Laminar thickness;
Optical coherence
tomography;
Enhanced depth
imaging
Summary
Purpose. — To investigate retinal nerve fiber layer (RNFL) thickness, anterior lamina cribrosa
depth (ALD) and laminar thickness (LT) in eyes with angioid streaks (AS) in comparison with
healthy eyes.
Methods. — Patients with AS (n = 32 eyes) and age-matched healthy subjects (n = 42 eyes) under-
went enhanced depth imaging with spectral domain optical coherence tomography of the optic
nerve head. RNFL thickness was obtained automatically by using the Heidelberg software. The
ALD was defined as the vertical distance between the Bruch’s membrane openings as reference
plane and the anterior border of the lamina cribrosa. The LT was measured as the distance
between the anterior and posterior borders of the lamina cribrosa. RNFL thickness, ALD and LT
were compared between the AS and healthy eyes adjusting for axial length.
Results. — The mean age was 51.7 ± 8.0 years for AS patients and 53.8 ± 10.2 years for control
subjects (P = 0.34). The mean RNFL thickness was 88.6 ± 17.6 m in AS eyes and 102.1 ± 8.3 m
in control eyes; the difference between the groups was significantly significant. ALD was
350.9 ± 70.8 m in AS eyes and 432.5 ± 82.1 m in control eyes, while LT was 166.3 ± 41.0 m
∗
Corresponding author.
E-mail address: dr.gkhndmr@gmail.com (G. Demir).
https://doi.org/10.1016/j.jfo.2018.12.015
0181-5512/© 2019 Elsevier Masson SAS. All rights reserved.