Journal français d’ophtalmologie (2019) 42, 586—591 Disponible en ligne sur ScienceDirect www.sciencedirect.com ORIGINAL ARTICLE Evaluation of lamina cribrosa in angioid streaks using spectral-domain optical coherence tomography enhanced depth imaging Evaluation par tomographie en cohérence optique en domaine spectral à l’imagerie à profondeur améliorée de la lame criblée chez des patients atteints des stries angioïdes G. Demir * , C. Altan , S. Cakmak , H. Topcu, D. Yasa, A. Demircan , Z. Alkin University of Health Sciences, Beyoglu Eye Training and Research Hospital, Bereketzade Cami Sok. No 2 Beyoglu, Istanbul, Turkey Received 26 October 2018; accepted 17 December 2018 Available online 14 May 2019 KEYWORDS Angioid streaks; Retinal nerve fiber layer thickness; Anterior lamina cribrosa depth; Laminar thickness; Optical coherence tomography; Enhanced depth imaging Summary Purpose. To investigate retinal nerve fiber layer (RNFL) thickness, anterior lamina cribrosa depth (ALD) and laminar thickness (LT) in eyes with angioid streaks (AS) in comparison with healthy eyes. Methods. Patients with AS (n = 32 eyes) and age-matched healthy subjects (n = 42 eyes) under- went enhanced depth imaging with spectral domain optical coherence tomography of the optic nerve head. RNFL thickness was obtained automatically by using the Heidelberg software. The ALD was defined as the vertical distance between the Bruch’s membrane openings as reference plane and the anterior border of the lamina cribrosa. The LT was measured as the distance between the anterior and posterior borders of the lamina cribrosa. RNFL thickness, ALD and LT were compared between the AS and healthy eyes adjusting for axial length. Results. The mean age was 51.7 ± 8.0 years for AS patients and 53.8 ± 10.2 years for control subjects (P = 0.34). The mean RNFL thickness was 88.6 ± 17.6 m in AS eyes and 102.1 ± 8.3 m in control eyes; the difference between the groups was significantly significant. ALD was 350.9 ± 70.8 m in AS eyes and 432.5 ± 82.1 m in control eyes, while LT was 166.3 ± 41.0 m Corresponding author. E-mail address: dr.gkhndmr@gmail.com (G. Demir). https://doi.org/10.1016/j.jfo.2018.12.015 0181-5512/© 2019 Elsevier Masson SAS. All rights reserved.