520 Perinatal outcome of pregnancies following in vitro fertilization and ovulation induction Tali Silberstein 1 , Eyal Sheiner 1 , Amalia Levy 2 , Avi Harlev 1 , Oshra Saphier 3 1 Soroka University Medical Center, Ben-Gurion University of the Negev, Department of Obstetrics and Gynecology, Faculty of Health Sciences, beer sheva, Israel, 2 Soroka University Medical Center, Ben-Gurion University of the Negev, Department of Epidemiology and Health Services Evaluation, Faculty of Health Sciences, beer sheva, Israel, 3 Sami Shamoon College of Engineering, Department of Chemical Engineering, beer sheva, Israel OBJECTIVE: To investigate pregnancy outcome in patient who conceived by assisted reproductive techniques. STUDY DESIGN: A retrospective population based study was con- ducted, comparing obstetrical complications and neonatal outcomes of singleton pregnancies conceived by in vitro fertilization (IVF; n¼1,296) and ovulation induction (n¼1,988) as compared to singleton pregnancies conceived spontaneously (n¼172,288). Multivariable models were constructed to control for confounders. RESULTS: A significant linear association (using the chi-square test for trends) was documented among the three groups in adverse outcomes such as gestational diabetes mellitus (GDM), severe preeclampsia and perinatal mortality (Table). In vitro fertilization and ovulation in- duction treatments were found to be independent risk factors for GDM and for lower gestational age at birth, using two different multiple logistic regression models controlling for confounders such as maternal age (adjusted OR¼1.77, 95% CI-1.52-2.07, P<0.001 and adjusted OR¼1.93, 95% CI-1.69-2.21, P<0.001; respectively). CONCLUSION: Pregnancies conceiving following assisted reproductive techniques are at an increased risk for adverse obstetric outcomes. The risk is higher for pregnancies following IVF compared with these conceived following ovulation induction. Pregnancy and perinatal complications in pregnancies following assisted reproductive techniques GDM - Gestational DM, PROM - Premature Rupture of Membranes. *P<0.05 using the chi-square test for trends. 521 Gestational age specific birth-weight curve for Asian Indian newborns Jagjit Teji 1 , Kamal El Deirawi 2 1 University of Chicago, Pediatrics, Chicago, IL, 2 University of Illinois, School of Nursing, Chicago, IL OBJECTIVE: To create a GA specific birth-weight (BWT) curve for Asian Indian (AI) newborns and compare it to the non-Hispanic white (NHW) babies. STUDY DESIGN: The linked birth/infant death perinatal data files from NCHS by CDC for the 8 years (1995 to 2002) were used in the analysis. The two races compared were the AI and the NHW. These curves were created for singleton births, delivered by mother without any medical risk factors during pregnancy, with birth weights for each specific GA >¼20 through 44 weeks. Data analysis was per- formed using SAS 9.1 and graph with Sigma Plot. RESULTS: Over the period from 1995 thru 2002 there were a total of about 32 million births in the US. During this period there were over 17 million NHW newborns and 167,000 AI newborns. After removing records without values the percentile curves were created with the remaining for GA vs BWT. It was observed that from 20 wks GA to 30 wks the BWT showed very little deviation among the two ethnicities but after the 30th wk of GA the curves diverged as the AI newborn BWT was 200 to 300 grams smaller at 5th, 25th, 50th 75th and the 95th percentiles. The median curve is presented for clarity in abstract. CONCLUSION: This is the first time presentation of the GA specific BWT curve for singleton AI newborns delivered by mothers without history of medical risk factors. These curves should serve as a norm for assessing GA specific BWT in AI newborns. 522 Population-based estimation of the preterm birth rate in Malawi: making every birth count Kjersti Aagaard 1 , Judy Levison 1 , Bertha Banda 2 , Andrew Chigayo 2 , Owen Chilaga 2 , Rose Chirwa 2 , Mary Nyondo 2 , David Gama 2 , Elizabeth Tamula 2 , R. Alan Harris 1 , Susan Ramin 1 , Peter Kazembe 2 , Henry Phiri 3 , Grace Chiudzu 3 1 Baylor College of Medicine, Obstetrics & Gynecology, Division of Maternal- Fetal Medicine, Houston, TX, 2 Baylor Center of Excellence, Saving Lives at Birth-Malawi, Lilongwe, Malawi, 3 Ethel Mutharika Maternity Wing, Kamuzu Central Hospital, Obstetrics & Gynecology, Lilongwe, Malawi OBJECTIVE: Preterm morbidities are attributed to 35-40% of the world’ s 3.1 million annual neonatal deaths (WHO). Globally, the highest estimated PTB rate is in the central African country of Malawi, reported at 18-22%. However, estimates vary by data www.AJOG.org Epidemiology, Ob Quality, Operative Obstetrics, Public Health, Infectious Disease, Academic Issues Poster Session III Supplement to JANUARY 2014 American Journal of Obstetrics & Gynecology S257