_____________________________________________________________________________________________________ *Corresponding author: E-mail: nr.ukibe@unizik.edu.ng; Journal of Pharmaceutical Research International 34(16B): 37-47, 2022; Article no.JPRI.77428 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Evidence of Risk Factors Associated with Autosomal Dominant Polycystic Kidney Disease in Newly Diagnosed Adult Hypertensive Patients in NAUTH Nnewi, Nigeria Nkiruka R. Ukibe a* , Anya O. Kalu b , Isaac P. Emeje a , Solomon N. Ukibe c , Gloria E. Ukibe b and Chigozie C. Obiekezie a a Department of Medical Laboratory Science, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, P. M. B 5025, Anambra State, Nigeria. b Department of Medicine, Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, P.M. B 5025, Anambra State, Nigeria. c Department of Medical Microbiology, Faculty of Basic Clinical Sciences, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, P.M. B 5025, Anambra State, Nigeria. Authors’ contributions This work was carried out in collaboration among all authors. Author NRU designed the study, wrote the first draft of the manuscript and wrote the protocol. Authors CCO, SNU and IPE performed the statistical analysis and managed the analysis of the study. OAK and GEU managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2022/v34i16B35745 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/77428 Received 02 November 2021 Accepted 07 January 2022 Published 28 February 2022 ABSTRACT Aims & objectives: Due to other chronic diseases that are associated with hypertension and kidney disease, little or no attention has been paid to the existence of polycystic kidney disease in Nigeria. The present study aimed at assessing the prevalence of some risk factors of ADPKD among hypertensive adult patients in NAUTH, Nnewi, Anambra State, Nigeria Study design: A cross-sectional and prospective study Place and Duration of Study: The study was carried out at Medical out-patient, cardiology and nephrology units of NAUTH Nnewi between February and June, 2019. Methodology: A total of 160(80 newly diagnosed hypertensive and 80 normotensive subjects) Original Research Article