28 ■ Cancer Nursing™, Vol. 25, No. 1, 2002 Weinrich et al
Interest in Genetic Prostate Cancer
Susceptibility Testing
Among African American Men
Six regions for prostate cancer genes have been identified, and it is anticipated
that prostate cancer susceptibility testing will be available in the future. This corre-
lational study identified predictors for interest in prostate cancer susceptibility test-
ing among African American men. Participants were 320 African American men
from the African American Hereditary Prostate Cancer Study and the South Car-
olina Prostate Cancer Education and Screening Study participated. Two questions
measured interest in genetic prostate cancer susceptibility testing and family his-
tory of prostate cancer. Chi-square analyses by family history as well as demo-
graphics (age, education, marital status) were performed.
Most of the men (277 [87%]) indicated an interest in genetic prostate cancer
susceptibility testing. Interest in undergoing testing did not vary by family his-
tory, age, or education. Marital status was the only significant demographic
predictor. Men who were married were significantly more likely to respond
with a “yes” to interest in prostate cancer susceptibility testing than were men
who were not married. The high “yes” response rate and the men’s confusion
between the genetic prostate cancer susceptibility testing and prostate cancer
screening highlight the need for public education once prostate cancer genes
are identified and available for public testing.
© 2002 Lippincott Williams & Wilkins, Inc., Philadelphia
Sally Weinrich, PhD, RN, FAAN
Charmaine Royal, PhD
Curtis A. Pettaway, MD
Georgia Dunston, PhD
Louise Faison-Smith, AD
Julie Hudson Priest, MSPH
Pamela Roberson-Smith, AS
Jacqueline Frost, DMS
Jean Jenkins, PhD, RN, FAAN
Karen Albiez Brooks, MS, CGC
Isaac Powell, MD
From the University of Louisville, Ky (Dr Weinrich); South Carolina Can-
cer Center, University of South Carolina, Columbia (Dr Weinrich and Ms Fai-
son-Smith); National Human Genome Center at Howard University, Wash-
ington, DC (Dr Royal); M.D. Anderson Cancer Center, Houston, Tex (Drs
Pettaway and Frost and Ms Roberson-Smith); Howard University College of
Medicine, Washington, DC (Dr Dunston); University of South Carolina,
Columbia (Ms Priest); National Cancer Institute at the National Naval Med-
ical Center, Bethesda, Md (Dr Jenkins); Genetic Center, School of Medicine,
University of South Carolina, Columbia, SC (Ms Brooks); and Wayne State
University, Detroit, Mich (Dr Powell).
Corresponding author: Sally P. Weinrich, PhD, RN, School of Nursing,
University of Louisville, KY 40292 (e-mail: sally.weinrich@louisville.edu).
Accepted for publication October 10, 2001.