www.wjpr.net Vol 6, Issue 6, 2017. 231 Alameen et al. World Journal of Pharmaceutical Research ASSESSMENT OF GLYCOSYLATED HEMOGLOBIN (HBA1C) IN POST RENAL TRANSPLANTATION PATIENTS-KHARTOUM STATE- SUDAN Rania Awad Abdallah Karar 1 , Ekram Hamza Mohamed Babiker 1 and Ayman Ali Mohammed Alameen 1 * 1 Department of Chemical Pathology, Faculty of Medical Laboratory Sciences, University of Khartoum –Sudan. ABSTRACT Background: Abnormal HbA1c and random blood glucose concentrations have been associated with post renal transplantation patients using Tacrolimus. Therefore, our study aimed to find out the relationship between HbA1c and Tacrolimus levels. Methodology: A case control study involving forty post renal transplantation patients and forty control subjects with different ages and gender. The study measuring HbA1c and Tacrolimus concentration in post renal transplantation patients. Result: Forty post renal transplantation patients and forty control subjects were studied. The mean±SD of duration was 2.22±2.39 years and Tacrolimus dose was 6.09±3.17 g/day. There is an elevation in HbA1c and Tacrolimus in post renal transplantation patients. Tacrolimus concentration Mean±SD was 6.71±1.89 g/ml and has no effect (P=0.0675) on HbA1c concentration of patients. Conclusion: The present study showed that there is no significant relationship between elevation of HbA1c and the concentration of Tacrolimus. KEYWORD: Glycosylated hemoglobin (HbA1c), D.M, Post kidney transplant, Tacrolimus. INTRODUCTION Diabetes has been shown to be closely related to post transplantation patients. [1] [2] Even they did not have diabetes after an organ transplant this type of diabetes is called new-„onset diabetes‟ after transplanting, it is also called (NODAT). New onset diabetes can occur as a World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 6, 231-236. Research Article ISSN 2277– 7105 *Corresponding Author Ayman Ali Mohammed Alameen Department of Chemical Pathology, Faculty of Medical Laboratory Sciences, University of Khartoum –Sudan. Article Received on 15 April 2017, Revised on 05 May 2017, Accepted on 25 May 2017 DOI: 10.20959/wjpr20176-8641