_____________________________________________________________________________________________________ *Corresponding author: E-mail: ddeepak72@iiphg.org; Journal of Pharmaceutical Research International 32(33): 40-47, 2020; Article no.JPRI.62323 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Acceptability and Perceptions of Generic Drugs among Patients, Pharmacists, and Physicians Krupali Patel 1 , Sandul Yasobant 1 , Jaykaran Charan 2 , Mayur Chaudhari 3 , Abhay Gaidhane 4 and Deepak Saxena 1,5* 1 Department of Epidemiology, Indian Institute of Public Health Gandhinagar (IIPHG), Gandhinagar, Gujarat, India. 2 Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India. 3 Department of Pharmacology, Government Medical College (GMC), Surat, Gujarat, India. 4 Department of Community Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, India. 5 Adjunct Faculty, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, India. Authors’ contributions This work was carried out in collaboration among all authors. Authors KP, SY, JC, MC, AG and DS designed the study, performed the statistical analysis, wrote the protocol, and wrote the draft of the manuscript. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2020/v32i3330948 Editor(s): (1) Dr. Wenbin Zeng, Central South University, China. Reviewers: (1) Mr. Someshwar Dattatraya Mankar, Pravara Rural College of Pharmacy, India. (2) Timanyuk Iryna, National University of Pharmacy, Ukraine. Complete Peer review History: http://www.sdiarticle4.com/review-history/62323 Received 02 September 2020 Accepted 07 November 2020 Published 09 December 2020 ABSTRACT Background: Generic drugs are the painstaking solution to deal with out of pocket expenditure however, the impact has not yet been seen in India. Thus, to understand the facilitators and barriers, this study aimed to gather evidence on the perception of the acceptability of generic drugs among patients, pharmacists, and physicians. Methods: The key informant interviews (KII) were conducted during 2017-2018 in Gujarat, India. A total of 25 (9 patients, 8 pharmacists, 8 physicians) KIIs were included in the thematic analysis. Results: Most of the patients knew about cheaper drugs are available in the market, but they perceived that those meant for poor people. Pharmacists talked about the profit from branded Original Research Article