Newly-diagnosed multiple myeloma patients carrying monoallelic deletion of the whole locus of immunoglobulin heavy chain gene have a better prognosis compared to those with t(4;14) and t(14;16) Adrian Duek 1 *, Luba Trakhtenbrot 1,2 *, Ninette Amariglio 1 ,2, Noam Benyamini 3 , Itay Zilbershats 4 , Chezi Ganzel 5 , Olga Shevetz 6 , Ronit Leiba 7 , Gabriela Rozic 1,8 , Arnon Nagler 1, and Merav Leiba 1,9 1 Division of Hematology and Bone Marrow Transplantation, The Chaim Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel-Aviv University, Israel 2 Cancer Research Center, The Chaim Sheba Medical Center, Tel Hashomer, Israel 3 Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel 4 Department of Hematology, Wolfson Medical Center, Holon, Israel 5 Department of Hematology, Shaare Zedek Medical Center, Jerusalem, Israel 6 Department of Hematology, Kaplan Medical Center, Rehovot, Israel 7 Biostatistics Ltd., Haifa, Israel 8 Ariel University, Ariel, Israel 9 Division of Hematology, Assuta Ashdod University Hospital, and Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel *These authors contributed equally to the study. Abbreviated Title: Better OS in MM with IGH monoallelic deletion This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/gcc.22738 This article is protected by copyright. All rights reserved.