25 13(3): 025-031 (2019) Journal of FisheriesSciences.com E-ISSN 1307-234X © 2019 www.fsheriessciences.com Review Article A Review on the Probiotc Efects on Haematological Parameters in Fish Sakyi Essien Michael 1- 3 , Emmanuel Delwin Abarike 1- 4 , Jia Cai 1-3* 1 College of Fishery, Guangdong Ocean University, Zhanjiang, China 2 Guangdong Provincial Key Laboratory of Pathogenic Biology and Epidemiology for Aquatic Animals, Zhanjiang, China 3 Key Laboratory of Control for Diseases of Aquatic Animals of Guangdong Higher Education Institutes, Zhanjiang, China, 4 Department of Fisheries and Aquatic Resources Management, University for Development Studies, Tamale-Ghana Received: 10.07.2019 / Accepted: 25.07.2019 / Published online: 31.07.2019 Abstract: Haematological indices are essential diagnostic tools used to evaluate the health status of fsh. Many publications have been stated by different works that qualitative and quantitative variations in haematological parameters; for instance White Blood Cells (WBCs), Red Blood Cells (RBCs), Haematocrit (Hct), Haemoglobin (Hb) content, Mean Corpuscular Haemoglobin Concentration (MCHC), Mean Corpuscular Haemoglobin (MCH) and Mean Corpuscular Volume (MCV) in fsh, offer an indication of the health status of the fsh. The uses of probiotics as biological control agents in aquaculture have replaced the usage of chemotherapeutics, is an approach in the build-up in aquaculture environments. In the cultured fsh, the use of probiotics in monospecies or multispecies forms has been reported to stimulate specifc and non-specifc immune parameters including lysozyme activities and phagocytic, expression of various cytokines as well as improvement of blood profles of many fsh increasing resistance diseases and to other environmental perturbations such as physiological stressors. Interestingly, many researchers have shown that haematological indices in fsh continue to offer a valuable diagnostic tool; and progress is made in establishing a reasonable range of values for blood parameters of different fsh species. Also, many interventions have shown that probiotics used in aquaculture have potential in improving blood profles of fsh; although there are not many summarised information regarding the effects of probiotics on haematological parameters in fsh. The purpose of this review is to synthesise the infuences of probiotics on haematological parameters in fsha. Keywords: Aquaculture; Blood cells; Haematology; Immune System; Probiotics; Physiological stressors * Correspondence to: Jia Cai, Fisheries College, Guangdong Ocean University, Huguang Yan East, Zhanjiang 524088, Guangdong Province, China, Tel: +86-759 2383507; E-mail: matrix924@126.com