Journal of Neuroradiology (2011) 38, 141—147 ORIGINAL ARTICLE Look for the nerves! MR neurography adds essential diagnostic value to routine MRI in pediatric practice: A pictorial overview Cherchez les nerfs ! La neurographie RM apporte des arguments diagnostiques essentiels à l’IRM de routine en pratique pédiatrique : une revue iconographique Laura Merlini a,* , Maria I. Vargas b , Mehrak Anooshiravani a , Magalie Viallon b , Joel Fluss c , Sylviane Hanquinet a a Unit of Pediatric Radiology, Geneva University Hospital HUG, 6, Willy-Donzé, 1205 Geneva, Switzerland b Unit of Neuroradiology, University Hospital of Geneva, 1205 Geneva, Switzerland c Unit Pediatric Neurology, University Hospital of Geneva, 1205 Geneva, Switzerland Available online 12 January 2011 KEYWORDS MR neurography; Children; Peripheral nerves; Diffusion tensor imaging Summary Purpose. — This study aimed to assess the feasibility of magnetic resonance (MR) neurography in children, and the potential roles of diffusion-weighted imaging (DWI) and fiber-tracking (FT) techniques. Methods. — Five pediatric patients (age range: 6—12 years) underwent magnetic resonance imaging (MRI) for various clinical indications: neurogenic bladder (case 1); persistent hand pain following minor trauma (case 2); progressive atrophy of the lower left extremity muscles (case 3); bilateral hip pain (case 4); and palpable left supraclavicular mass (case 5). All studies were performed using a 1.5-T Avanto MRI scanner (Siemens, Erlangen, Germany). The protocol included 3D T2-weighted STIR and SPACE imaging, T1-weighted fat-saturation post-gadolinium imaging and diffusion tensor imaging (DTI) with tractography. ADC (N × 10 -3 mm 2 /s) and FA val- ues were calculated from regions of interest (ROIs) centered on the nerves. Nerve-fiber tracks were calculated using a fourth-order Runge-Kutta algorithm (NeuroD software). Results. — MR neurography allowed satisfactory visualization of all neural structures, and FA and ADC measurements were feasible. The final diagnoses were Tarlov cysts, median-nerve compression, sciatic perineurioma, Charcot-Marie-Tooth disease and plexiform neurofibroma in a patient with NF-1. Corresponding author. Tel.: +41 22 37 27 020; fax: +41 22 37 27 080. E-mail address: Laura.Merlini@hcuge.ch (L. Merlini). 0150-9861/$ – see front matter © 2010 Elsevier Masson SAS. All rights reserved. doi:10.1016/j.neurad.2010.09.006 © 2021 Elsevier Masson SAS. Tous droits réservés. - Document téléchargé le 03/12/2021 Il est interdit et illégal de diffuser ce document.