Research Article
An External Validation Study of the Oakland and Glasgow-
Blatchford Scores for Predicting Adverse Outcomes of Acute
Lower Gastrointestinal Bleeding in an Asian Population
Duc Trong Quach ,
1,2
Uyen Pham-Phuong Vo,
1,2
Nguyet Thi-My Nguyen,
3
Ly Thi-Kim Le,
2
Minh-Cong Hong Vo,
2
Phat Tan Ho,
3
Tran Ngoc Nguyen,
4
Phuong Kim Bo,
4
Nam Hoai Nguyen,
5
Khanh Truong Vu,
5
Manh Van Dang,
6
Minh Cao Dinh,
6
Thai Quang Nguyen,
7
Xung Van Nguyen,
7
Suong Thi-Ngoc Le,
8
and Chi Pham Tran
8
1
Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam
2
Department of Gastroenterology, Gia-Dinh People’s Hospital, Vietnam
3
Department of Gastroenterology, Cho-Ray Hospital, Vietnam
4
Department of Gastroenterology, Can-Tho Central Hospital, Vietnam
5
Department of Gastroenterology, Bach-Mai Hospital, Vietnam
6
Department of Gastroenterology, Dong-Nai General Hospital, Vietnam
7
Department of Gastroenterology, Da-Nang General Hospital, Vietnam
8
Department of Gastroenterology, Hue Central Hospital, Vietnam
Correspondence should be addressed to Duc Trong Quach; drquachtd@gmail.com
Received 26 May 2020; Revised 6 December 2020; Accepted 24 December 2020; Published 6 January 2021
Academic Editor: Konstantinos Triantafyllou
Copyright © 2021 Duc Trong Quach et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.
Aims. This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing
these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a
Vietnamese population. Methods. A multicenter cohort study was conducted on ALGIB patients admitted to seven hospitals
across Vietnam. The adverse outcomes of ALGIB consisted of blood transfusion; endoscopic, radiologic, or surgical
interventions; severe bleeding; and in-hospital death. The Oakland and GBS scores were calculated, and their performance was
compared with that of SALGIB, a locally developed prediction score for adverse outcomes of ALGIB in Vietnamese, based on
the data at admission. The accuracy of these scores was measured using the area under the receiver operating characteristic
curve (AUC) and compared by the chi-squared test. Results. There were 414 patients with a median age of 60 (48–71). The rates
of blood transfusion, hemostatic intervention, severe bleeding, and in-hospital death were 26.8%, 15.2%, 16.4, and 1.4%,
respectively. The SALGIB score had comparable performance with the Oakland score (AUC: 0.81 and 0.81, respectively; p =
0:631) and outperformed the GBS score (AUC: 0.81 and 0.76, respectively; p =0:002) for predicting the presence of any adverse
outcomes of ALGIB. All of the three scores had acceptable and comparable performance for in-hospital death but poor
performance for hemostatic intervention. The Oakland score had the best performance for predicting severe bleeding.
Conclusions. The Oakland and SALGIB scores had excellent and comparable performance and outperformed the GBS score for
predicting adverse outcomes of ALGIB in Vietnamese.
1. Introduction
The prevalence of acute lower gastrointestinal bleeding
(ALGIB) which leads to hospitalization has been increasing
over the last twenty years [1]. Although there are several risk
scores for predicting adverse outcomes of ALGIB, most of
these scores fail to accurately predict outcomes when exter-
nally validated in other populations [2, 3]. The Oakland score
Hindawi
Gastroenterology Research and Practice
Volume 2021, Article ID 8674367, 7 pages
https://doi.org/10.1155/2021/8674367