Indian Journal of Pathology and Oncology 2020;7(4):561–566 Content available at: https://www.ipinnovative.com/open-access-journals Indian Journal of Pathology and Oncology Journal homepage: www.ijpo.co.in Original Research Article Histopathological study of ovarian tumours in a tertiary healthcare centre of southern Rajasthan Pranshu Sharma 1 , Pranveer Singh Rao 1, *, Narendra Mogra 2 , Khushbu Talreja 3 1 Dept. of Pathology, Ananta Institute of Medical Sciences, Rajsamand, Rajasthan, India 2 Dept. of Pathology, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India 3 Dept. of Pathology, Government Medical College, Kota, Rajasthan, India ARTICLE INFO Article history: Received 14-02-2020 Accepted 22-05-2020 Available online 19-11-2020 Keywords: Ovarian tumors Germ cell Borderline Teratoma Serous Mucinous ABSTRACT Aims and Objectives: Ovarian tumors are an increasing cause for morbidity and mortality worldwide. The present study was conducted in a tertiary healthcare centre of southern Rajasthan to determine the incidence of various histological and morphological variants of ovarian tumour, their clinical presentation and age distribution. Material and Methods: The study was performed in two tertiary healthcare centre of southern Rajasthan and included 130 specimens of ovary received in the pathology department of two centers. The specimens were subjected to critical gross as well as histopathological study. Routine paraffin sections with H & E staining were seen. The clinical as well as histological findings were compiled on proforma and then subjected to analysis. Results: Total 130 patients were included in the study with the age range from 10 years to 90 years. Maximum patients were from age group 41-50 years (24.61%). In the present study, abdominal pain (46.1%) was the most common presenting complaint followed by mass per abdomen with irregular periods (10.7%). Majority of the ovarian tumours belonged to benign tumours (66.92%) followed by malignant tumours (28.46%). As per WHO classification, surface epithelium tumours were found to be the commonest variety (76.12%), followed by Germ cell tumour (18.46%). Three cases of metastatic tumours to ovaries were also diagnosed in the present study. Among the various known subtypes of ovarian tumours, serous cystadenoma (30.77%) was found to be the most common subtype followed by benign cystic teratoma (16.92%) and then serous cystadenocarcinoma (13.85%). Conclusion: Benign ovarian tumours are more common than malignant or borderline tumours. Among the histopathological subtypes of ovarian tumours, surface epithelial tumours are the commonest type followed by germ cell tumours. Differentiation between benign and malignant tumours is important to assure proper management and recovery. Similar studies with greater sample size are advisable in future. © This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 1. Introduction The ovaries are paired intra-pelvic organ of female reproductive system involved with many important functions in the body. The main function of the ovary is to produce ova to implant after fertilization in the endometrium. It also functions as an endocrine gland in the development of secondary sexual characters as well as their * Corresponding author. E-mail address: docpages11@gmail.com (P. S. Rao). maintenance. Thus ovary is always in a dynamic state. 1 Ovary being a complex and unique organ has been described to be involved by wide varieties of neoplasms. This has been due to the presence of many cell types in this organ under normal conditions, including some cells which are multipotent to totipotent. No organ of the body except ovary gives rise to such a galaxy of neoplasms. Ovarian tumours have been rightly termed as complex wide spectrum of diseases rather than a single entity. 2 https://doi.org/10.18231/j.ijpo.2020.112 2394-6784/© 2020 Innovative Publication, All rights reserved. 561