* Corresponding author: Deliverance Brotobor Department of Nursing Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria. Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0. Knowledge, attitude and utilization of evidence-based practice among nurses in Tertiary Hospitals Sarah O. Bankole 1 , Clementina U. Nwankwo 2 , Deliverance Brotobor 3, * and Anulika Johnson Afonne 2 1 Department of Clinical Nursing, Irrua Specialist Hospital, Irrua, Edo State, Nigeria. 2 Department of Nursing Science, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria. 3 Department of Nursing Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria. World Journal of Advanced Research and Reviews, 2022, 13(03), 063–072 Publication history: Received on 07 January 2022; revised on 27 February 2022; accepted on 01 March 2022 Article DOI: https://doi.org/10.30574/wjarr.2022.13.3.0140 Abstract The increase demand for healthcare, technology advancement and knowledge explosion has necessitated a paradigm shift from nursing practice which was based on intuition and tradition to evidence-based practice in nursing. EBP is a concept that has not been widely utilized by most nurses working in clinical setting in Nigeria according to previous documentation. Therefore, this study aimed to explore and describe the perception and utilization of evidence-based practice among nurses working in Federal Teaching Hospital in Edo state. A cross sectional descriptive survey design was adopted to assess the perception and utilization of evidence-based practice among nurses working in tertiary hospitals in Nigeria; Irrua Specialist Teaching Hospital and University of Benin Teaching Hospital both in Edo State. A sample size of 334 nurses working in the two teaching hospitals in Edo state was obtained using a proportionate sampling technique. The instrument used for data collection was a standardized tool titled “evidence-based practice questionnaire. Data collected were coded and analyzed using both descriptive and inferential statistics of chi-square to summarize and describe the characteristics of the respondents and establish the relationships of the study variables and the respondents’ demographic characteristics. The findings of the study revealed that majority of the nurses are RN/RM (51.8%, n=158) while only (25.5%, n=87) are degree holder. The study further revealed that majority of the respondents has a good knowledge of evidence-based practice (90.2%, n=275). There was a significant association between the nurses’ years of working experience and their knowledge of EBP (p = .030). There was also a sign ificant relationship between knowledge of EBP and it utilization (p=.001). Hence, there is need for the hospital managements and nursing leader’s to motivate nurse to continue to use evidence-based practice as a tool to provide nursing services that is safe, sound, high quality, cost effective. Furthermore, evidence-based practice culture and mentors should be created within the hospitals. Keywords: Knowledge; Attitude; Utilization; Evidence-Based Practice; Nurses 1. Introduction The global challenge faced by health care practitioners and health care institutions today is the non-provision of evidence-based, cost effective and quality care that will improve practice and patient outcome [1, 2]. For many years, evidence-based practice (EBP) has been a major priority in many countries. The World Health Organization (WHO) and the European Commission emphasized that health and social services should be based on best research evidence because it serves as key to delivering the highest quality of healthcare in clinical setting [3]. However, Nurses being the largest healthcare professional group that provides healthcare services to clients in most health care sectors needs a lot of research evidence to support their practice [4,5]. Consequently, nurses are expected to provide care services with the