This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/dta.2327 This article is protected by copyright. All rights reserved. Semi-quantitative Analysis of Tramadol, Dextromethorphan and Metabolites in Decomposed Skeletal Tissues by Ultra Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry (UPLC-qTOF-MS) H. M. Cornthwaite ‡ L. Labine † and J. H. Watterson* †‡ , ‡Department of Chemistry & Biochemistry and †Department of Forensic Science Laurentian University, 935 Ramsey Lake Rd Sudbury, Ontario, Canada P3E 2C6 *Author to whom correspondence should be addressed: jwatterson@laurentian.ca