Isolation and Characterization of hydroxyapatite from Giant Travelly (GT) Fish bone Waste as a Biocheramic Materials for Aplication of Implant Dental Body Melsiani R F Saduk 1 , Duran Hore 1 , Agustinus Deka Betan 1 , Fransisko Piri Niron 1 {melsianisd@gmail.com, yolan_yoel@yahoo.com , agustinusbetan@gmail.com, fransiskoniron@yahoo.co.id} Politeknik Negeri Kupang, Jl Adi Sucipto PO Box 139 Penfui Kupang 1,2,3,4 Abstract. The use of dental implants is now wider, and has various types of dentures. Today, titanium is still the 'gold standard' for the manufacture of dental implants because of the high long-term clinical success rate. However, concerns arise from titanium metals that have caused allergic reactions and sensitivity. Therefore, the purpose of this study was to produce HA isolates that have characteristics that meet the requirements of proactive raw materials in making biochemical body implants through isolation and characterization of HA from GT fish bone waste. The planned research activities include preparation of fish bone test samples, HA characterization with FTIR, XRD, and XRF. Based on XRF analysis it was found that CaO compound had the biggest percentage which was 68,96%. FTIR analysis indicate the presence of OH groups, CO3 and PO4. And xrd analysis shows that the crystallite phase formed is hexagonal. Keywords: bioceramics, GT fish bone, hydroxyapatite, dental implants 1 Introduction The use of dental implants (dental implants) is now increasingly widespread, and is the best alternative of various types of dentures. The principle of dental implants Associated with other types of dentures that improve the function of mastication. The difference is that there are only different types of dentures available, while the implant consists of two parts, namely the infrastructure that is moved in the bone and is being prepared to contain the tooth root and the superstructure that functions to activate the crown. Currently titanium metal is still the 'gold standard' for the manufacture of dental implants due to the high level of long-term clinical success. The implant material should ideally meet the requirements: biocompatible, corrosion resistant, fracture resistant. The implant design principle must be in accordance with the physical properties of the implant material. The materials used for the manufacture of dental implants can be categorized according to their chemical composition or the biological response produced when the material is implanted into the body. From a chemical point of view, dental implants can be made of metal, ceramics, or polymers [1] Research on alternative materials to replace bone and tooth damage has been done, one of which is the use of synthetic synthetic materials, namely bioceramics, polymers or ICESC 2019, October 18-19, Indonesia Copyright © 2019 EAI DOI 10.4108/eai.18-10-2019.2289971