Section Physiology Distribution of ABO, Rh Blood Groups amongst the Medical Undergraduate Students in a Tertiary Care Hospital Sameer Srivastava 1 , Parag Rastogi 1* 1 Assistant Professor, Dept. of Physiology, Venkateshwara Institute of Medical Sciences, Gajraula, Dist. Amroha, UP International Archives of BioMedical and Clinical Research | Oct – Dec 2017| Vol 3| Issue 4 130 Original Article ABSTRACT______________________________________________________________ Background: The importance of knowing blood groups is very essential for every individual. Therefore, in order to promote the awareness of the same in a medical college among medical undergraduate students will have impact on them. Therefore, this study was conducted to document the frequency of ABO &Rh (D) blood groups. Methods: This prospective study was conducted on first year medical undergraduate students in the department of Physiology at VIMS, Gajraula, U.P. A total of 80 subjects of both genders were enrolled on the basis of inclusion and exclusion criteria. A finger prick blood sample of both genders was tested for ABO and Rh (D) blood groups by routine slide method. Result: Blood group ‘O’ was dominant in both Rh⁺ and Rh⁻ subjects followed by group B, A and AB occurs with lowest frequency in both males and females. The percentage of Rh⁺ and Rh⁻ subjects was 95% and 5% respectively. Conclusion: the frequency of ABO blood groups in both Rh⁺ and Rh⁻ subjects in Uttar Pradesh was O>B>A>AB. Rh⁺ blood group was much more common than Rh⁻ blood group. Key Words: ABO, Rh, blood groups. DOI:10.21276/iabcr.2017.3.4.32 Article History Received: 26.08.17 Accepted: 12.09.17 *Address for Correspondence Dr. Parag Rastogi, Assistant Professor, Dept. of Physiology, VIMS, Gajraula. Copyright: © the author(s) and publisher. IABCR is an official publication of Ibn Sina Academy of Medieval Medicine & Sciences, registered in 2001 under Indian Trusts Act, 1882. This is an open access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. INTRODUCTION_____________________ Human population genetics is primarily concerned with the study of the nature of the biological variations in human population which in turn will help us in understanding the nature and process of the ongoing evolution. India with its vast amount of diversity presents a unique opportunity to delineate human variation based on sociocultural, linguistic, ethnic and geographical criteria. Immunological properties of red blood cells generally described as blood groups. The vast interest arising out of a blood group lies in the fact that the character of the ABO, Rh blood groups is exclusively an integrally heritable, genetically determined at conception of life and remains fixed for life. Hence its frequency distribution follows a known pattern governed by gene transmission from generation, and varies with the race and geographical distribution of human beings. Summarising the distribution of ABO polymorphism in Indian populations, Bhasin & Walter (2001) observed that the frequency of allele ABO*B predominates ABO*A with general frequency of 0.233 and 0.186 respectively with an exception of eastern Himalaya region. An increase in ABO*A and ABO*B and decrease in ABO*O allele frequency from South to North of India is also reported by them. [1] The local figure on the frequency of the ABO blood groups Access this article online Website: www.iabcr.org Quick Response code DOI: 10.21276/iabcr.2017.3.4.32 How to cite this article: Srivastava S, Rastogi P. Distribution of ABO, Rh Blood Groups Amongst the Medical Undergraduate Students in a Tertiary Care Teaching Hospital. Int Arch BioMed Clin Res. 2017;3(4):130-131. Source of Support: Nil, Conflict of Interest: None