_____________________________________________________________________________________________________ *Corresponding author: E-mail: pt.mpiana@unikin.ac.cd, ptmpiana@gmail.com; Annual Research & Review in Biology 37(6): 28-36, 2022; Article no.ARRB.87349 ISSN: 2347-565X, NLM ID: 101632869 Anthelmintic and Antioxidant Activities, Phytochemical Profile and Microscopic Features of Senna alata Collected in the Democratic Republic of Congo Giresse N. Kasiama a , Adam Ikey a , Carlos N. Kabengele a , Jason T. Kilembe a , Etienne N. Matshimba a , Juvenal M. Bete a , Prudent B. Bahati b , Clément L. Inkoto c , Paulin K. Mutwale b , K. N. Ngbolua c , Damien S. T. Tshibangu a , Dorothée D. Tshilanda a and Pius T. Mpiana a* a Département of Chemistry and Industry, Sciences Faculty, University of Kinshasa, B.P. 190, Kinshasa XI, Democratic Republic of the Congo. b Phamceutical Sciences Faculty, University of Kinshasa, B.P. 212, Kinshasa XII, Democratic Republic of the Congo c Département of Biology, Sciences Faculty, University of Kinshasa, B.P. 190, Kinshasa XI, Democratic Republic of the Congo. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/ARRB/2022/v37i630513 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/87349 Received 12 March 2022 Accepted 23 May 2022 Published 31 May 2022 ABSTRACT Aim: The objective of this study was to determine the phytochemical profile of Senna alata LINN using chemical screening in solution and thin-layer chromatography, and to assess the antioxidant and anthelmintic activities of the plant’s aqueous extracts. Methodology: All the analyses performed in this study were, respectively, done as described by the standard protocols. These were: the microscopic examination of the plant powders performed using a light microscope, the search for secondary metabolites carried out by chemical screening in solution and by thin-layer chromatography, the determination of the secondary metabolites, and the Original Research Article