1 Accepted Manuscript Accepted Manuscript (Uncorrected Proof) Title: Use of the Longitudinal Model of Variance Components to Determine Hyper-Connectivity in Patients with Severe Traumatic Brain Injury Using Rs_fMRI Data Running Title: Determine Hyper-Connectivity in Patients with TBI Authors: Keyvan Olazadeh 1 , Nasrin Borumndnia 2 , Mahin Habibi 3 , Hamid Alavi Majd 1, * 1. Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2. Urology and Nephrology Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 3. Department of Biostatistics Faculty of Medical Sciences Tarbiat Modares University, Tehran, Iran. *Corresponding Author: Email: alavimajd@gmail.com To appear in: Basic and Clinical Neuroscience Received date: 2021/10/15 Revised date: 2022/04/10 Accepted date: 2022/04/16