How to Cite: Elwasif, S. M., Megahed, M. O., Elmoghazy, G., & Derbalah, S. A. (2022). Unravelling the role of MPV/platelets count on vascular access function among haemodialysis Egyptian patients: A retrospective single centre study. International Journal of Health Sciences, 6(S3), 8060–8070. https://doi.org/10.53730/ijhs.v6nS3.7775 International Journal of Health Sciences ISSN 2550-6978 E-ISSN 2550-696X © 2022. Manuscript submitted: 27 March 2022, Manuscript revised: 18 April 2022, Accepted for publication: 9 May 2022 8060 Unravelling the role of MPV/platelets count on vascular access function among haemodialysis Egyptian patients: A retrospective single centre study Salwa Mahmoud Elwasif Fellow of Internal Medicine and Nephrology, Urology and Nephrology Centre, Mansoura University, Egypt ORCID: 0000-0001-5239-5567 *Corresponding author email: drsalwa22000@yahoo.com Mohamed Osama Megahed Assistant Lecturer of Internal Medicine, Damietta University, Egypt ORCID: 0000-0003-2399-5752 Ghalia Elmoghazy Fellow of Nursing, Quality Manager, Urology and Nephrology Centre, Mansoura University, Egypt ORCID: 0000-0002-5813-0911 Safaa Awad Derbalah Fellow of Medical Analysis, Clinical Pathology Unit, Urology and Nephrology Centre, Mansoura University, Egypt ORCID: 0000-0003-4021-8234 Abstract---Background and Aims: End-stage kidney disease (ESKD) is a global health problem. It necessitates renal replacement therapy via renal transplantation, peritoneal dialysis, or hemodialysis. Vascular access is mandatory for every patient maintained on hemodialysis. It is a prerequisite for adequate hemodialysis (HD). Platelets play the most important role in securing vascular access function. Patients and Methods: A retrospective cohort study was conducted on 87 patients who underwent intermittent HD via arteriovenous fistula (AVF). Patients were divided into two groups. Group1 (Study group): patients with recent thrombosed AVF within a week of laboratory investigation. Group2 (Control group): patients with well-functioning AVF Evaluation of patients: Results: The mean platelet volume (MPV), Plateletcrit (PCT), and platelet diameter width (PDW) were 10.43, 0.222, and 13.56 in the study group respectively while in the control