Vol.:(0123456789) 1 3
Conservation Genet Resour
DOI 10.1007/s12686-017-0728-y
TECHNICAL NOTE
Single nucleotide polymorphism markers for analysis of historical
and contemporary samples of Arctic char (Salvelinus alpinus)
Magnus W. Jacobsen
1
· Camilla Christensen
1
· Rikke Madsen
1
· Rasmus Nygaard
2
·
Bjarni Jónsson
3
· Kim Præbel
4
· Michael M. Hansen
1
Received: 9 March 2017 / Accepted: 10 March 2017
© Springer Science+Business Media Dordrecht 2017
et al. 2012), and it is predicted that Arctic regions will
experience the most drastic temperature increases (Hinz-
man et al. 2005). Arctic char (Salvelinus alpinus) is a sal-
monid fsh that is distributed across cold regions of the
Northern Hemisphere. The species is considered signif-
cantly vulnerable to the efects of climate change, and it has
been estimated that by 2100 it may have lost >70% of its
range in Sweden (Hein et al. 2012). In Arctic regions like
Greenland and Canada the species is an important target for
local fsheries and is often the top predator in lakes and riv-
ers. Due to its ecological and economic importance, moni-
toring eforts are warranted that can readily detect negative
changes in key demographic parameters. Genetic monitor-
ing (Schwartz et al. 2007) fulflls these requirements, and
if historical samples are available this furthermore allows
for retrospective monitoring (Nielsen and Hansen 2008).
Here we present a resource of SNPs (Single nucleotide
polymorphisms), identifed using ddRAD (double digest
Restriction site Associated DNA) sequencing, and adapted
for the Fluidigm Biomark platform (Fluidigm Corporation,
San Francisco, CA, USA). We validate the markers by ana-
lyzing contemporary and historical samples of anadromous
and landlocked populations from Greenland, Iceland and
Norway.
Materials and methods
ddRAD sequencing
ddRAD sequencing (Peterson et al. 2012) using the restric-
tion enzymes SbfI and MspI was conducted for fve popula-
tions from the Nuuk Fjord region, Greenland (Fig. 1) and
for six family crosses involving parent fsh from one of the
populations, Kobbeford. Ilumina HiSeq2000 sequencing
Abstract Arctic regions are predicted to experience dras-
tic temperature increases in the future, which may impact
species negatively by changing their environments and
habitats. One such species is the Arctic Char (Salvelinus
alpinus), which is an important target for local fsheries and
the top predator in many freshwater systems. Here we pre-
sent 53 SNPs for population genetic inferences in the spe-
cies. They are tested in contemporary and historical sam-
ples and will provide a useful resource for future studies of
genetic structure and for genetic monitoring of Arctic char
populations.
Keywords SNPs · ddRAD sequencing · Arctic char ·
Salvelinus alpinus · Genetic monitoring · Historical
samples
Introduction
Anthropogenic climate change is considered one of the
most severe challenges to wild plants and animals (Bellard
Electronic supplementary material The online version of this
article (doi:10.1007/s12686-017-0728-y) contains supplementary
material, which is available to authorized users.
* Magnus W. Jacobsen
magnus.jacobsen@bios.au.dk
1
Department of Bioscience, Aarhus University, Ny
Munkegade 114, 8000 Aarhus C, Denmark
2
Greenland Institute of Natural Resources, Kivioq 2, P.O.
Box 570, 3900 Nuuk, Greenland
3
Northwest Iceland Nature Research Centre, Adalgata 2,
550 Saudárkrókur, Iceland
4
UiT The Arctic University of Norway, 9037 Tromsø, Norway