Research Article Received: 9 January 2014 Revised: 24 April 2014 Accepted article published: 19 May 2014 Published online in Wiley Online Library: (wileyonlinelibrary.com) DOI 10.1002/jsfa.6742 Tocopherol and tocotrienol contents of different varieties of rice in Malaysia Balakrishnan Shammugasamy, Yogeshini Ramakrishnan, Hasanah M Ghazali and Kharidah Muhammad * Abstract BACKGROUND: The present study examined the contents of tocopherols and tocotrienols and their distribution in 58 different varieties of whole rice cultivated in Malaysia. The analytical method used was saponification of samples followed by dispersive liquid–liquid microextraction and reverse phase high-performance liquid chromatography. RESULTS: The total vitamin E contents of different varieties of whole rice ranged between 19.36 and 63.29 mg kg -1 . Contents of vitamin E isomers varied among rice varieties both within and between grain color groups. Black-pigmented rice showed signifi- cantly higher mean contents of -tocopherol, -tocopherol and -tocotrienol than non-pigmented rice and red-pigmented rice. Red-pigmented rice had significantly lower mean contents of -tocotrienol and total vitamin E than non-pigmented rice. The mean contents of -tocotrienol and total vitamin E in non-pigmented rice, however, were similar to those in black-pigmented rice. -Tocotrienol was the predominant form of vitamin E isomer in all analyzed varieties. The Pearson correlations among vitamin E isomers and total vitamin E content of whole rice were also studied. CONCLUSION: This study provides information on vitamin E content of different rice varieties that would be beneficial for decision making in genetic breeding of bioactive compound-rich rice varieties. © 2014 Society of Chemical Industry Keywords: tocopherol; tocotrienol; rice varieties; Malaysia: microextraction INTRODUCTION Rice (Oryza sativa L.) is one of the most important cereal commodi- ties in the world and a main staple food in many countries, espe- cially in Asia. Annual rice production is growing steadily and the estimated global production of rice for the year 2012 was 486.9 million tonnes (milled basis), which included 441.6 million tonnes (milled basis) produced in Asian countries. 1 Rice is consumed mostly as milled rice; however, consumption of non-milled or whole rice is increasing with the growing knowledge of its health benefits. Whole rice contains the bran, germ and endosperm, whereas in milled rice the bran and the germ of the rice ker- nel are removed during the milling process. The endosperm con- sists mainly of carbohydrate and contains lower amounts of lipid and fiber than the germ and bran. The majority of bioactive com- pounds of whole rice are present in the bran and germ fractions. Whole rice contains a wide range of bioactive compounds such as vitamin E (tocopherols and tocotrienols), -oryzanols, phenolic acids, flavonoids and phytic acid. 2 4 In addition, black-pigmented rice and red-pigmented rice have been reported to contain antho- cyanins and proanthocyanidins respectively. 5,6 These bioactive compounds have been associated with the possibility to reduce the risk of developing chronic diseases, including cardiovascu- lar disease, type 2 diabetes, obesity and cancer. 7 9 Among these bioactive compounds, vitamin E (tocopherols and tocotrienols) and -oryzanols are the major and most characterized com- pounds. Rice and other cereals are the main sources of vitamin E. 10,11 The highest content of vitamin E was found in rice bran, fol- lowed by whole rice and milled rice. 4,12 It is noteworthy that the content of vitamin E in milled rice is even lower than that in the rice husk. 12 The rise in health awareness and demand for health-promoting food has encouraged the cultivation and development of some special rice varieties that are rich in bioactive compounds. One of the features in determining the quality of rice is the content of vita- min E, which is variable and dependent on rice genetic and envi- ronmental conditions. 13 The vitamin E contents of whole rice of different varieties found in Taiwan, 12 South Korea, 4,14 Venezuela, 15 Brazil 16 and Sri Lanka 17 have been reported. The contents of vita- min E in bran of rice varieties from Japan 3 and the southern USA 13 were also studied. However, information on the vitamin E content of Malaysian rice varieties is lacking even though rice is one of the main agricultural commodities of Malaysia. The Malaysian Agricultural Research and Development Institute (MARDI) plays a significant role in developing new high-yielding and disease-resistant rice through specific breeding programs. MARDI has been breeding many new varieties, and up to 42 varieties of rice have been released for commercial cultivation in Malaysia since the first variety was introduced in 1964. Apart from that, there are also many wild rice varieties grown traditionally Correspondence to: Kharidah Muhammad, UPM-BERNAS Research Laboratory, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor Darul Ehsan, Malaysia. E-mail: kharidah@upm.edu.my UPM-BERNAS Research Laboratory, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor Darul Ehsan, Malaysia J Sci Food Agric (2014) www.soci.org © 2014 Society of Chemical Industry