Accepted Manuscript Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway Aleksandra Wojtala, Agnieszka Karkucinska-Wieckowska, Vilma A. Sardao, Joanna Szczepanowska, Pawel Kowalski, Maciej Pronicki, Jerzy Duszynski, Mariusz R. Wieckowski PII: S1567-7249(16)30252-5 DOI: doi: 10.1016/j.mito.2017.07.002 Reference: MITOCH 1199 To appear in: Mitochondrion Received date: 20 November 2016 Revised date: 22 May 2017 Accepted date: 13 July 2017 Please cite this article as: Aleksandra Wojtala, Agnieszka Karkucinska-Wieckowska, Vilma A. Sardao, Joanna Szczepanowska, Pawel Kowalski, Maciej Pronicki, Jerzy Duszynski, Mariusz R. Wieckowski , Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway, Mitochondrion (2017), doi: 10.1016/j.mito.2017.07.002 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.