Open Access Library Journal How to cite this paper: Kamangu, E.N., et al. (2015) Prevalence of Malaria Infection among People Living with HIV in Kin- shasa. Open Access Library Journal, 2: e1077. http://dx.doi.org/10.4236/oalib.1101077 Prevalence of Malaria Infection among People Living with HIV in Kinshasa Erick Ntambwe Kamangu 1,2* , Hypolite Mavoko Muhindo 3,4 , Carole Weba Wapa-Kamangu 2 , Hippolyte Nani-Tuma Situakibanza 3,5 1 Molecular Biology Unit, Department of Basic Sciences, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo 2 Research Group “Focus HIV/AIDS”, Kinshasa, Democratic Republic of Congo 3 Department of Tropical Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo 4 International Health Unit, University of Antwerp, Antwerp, Belgium 5 Department of Infectious Diseases, University Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo Email: * Erick.kamangu@unikin.ac.cd Received 22 January 2015; accepted 6 February 2015; published 12 February 2015 Copyright © 2015 by authors and OALib. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract Background: Infection with the Human Immunodeficiency Virus (HIV) and malaria are two infec- tious diseases which are among the leading causes of morbidity and mortality in Sub-Saharan Africa and each a major public health problem. Data on malaria infection among people living with HIV (PLHIV) are poorly defined in Kinshasa as there are very few studies available on the subject. Objective: To determine the rate of co-infection HIV/malaria in Kinshasa to improve the care of PLHIV, this study was initiated to update the data. Methodology: This study was a prospective co- hort. 123 volunteers participated in this study in the third month. 114 patients completed the 6- month visit. Malaria diagnosis by microscopy was performed at the two medical visits. A sample of 5 ml of blood was also drawn in a tube with EDTA for the determination of viral load and measur- ing the level of CD4 T cells. Results: In the third month of Antiretroviral Therapy (ART), we had 123 PLHIV (78 women and 45 men). Viral loads (VL) ranged from 390.79 copies/ml (2.59 log10) and 38546691.53 copies/ml (6.59 log10). The CD4 ranged between 90 and 547 cells/mm 3 . 25 patients (20.33%) were positive for malaria. At 6th month of ART, there were 114 patients (75 women and 39 men). The CV of the population ranged from 0 copies/ml and 2693671.54 copies/ml (6.43 log10). The CD4 at 6th month were in the range between 421 and 984 cells/mm 3 . 20 patients (17.54%) presented positive thick smear for malaria. Conclusion: The prevalence rate of HIV/ malaria co-infection varies between 17.54% and 20.33% in Kinshasa. Keywords HIV, Malaria, Co-Infection, Kinshasa, Democratic Republic of Congo * Corresponding author.