Elucidation of Factor VIII Activity Pharmacokinetics: a Pooled Population Analysis in Hemophilia A Patients Treated with Moroctocog Alfa João A. Abrantes 1 , Elisabet I. Nielsen 1 , Joan Korth-Bradley 2 , Lutz Harnisch 3 , Siv Jönsson 1 From: 1 Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden, 2 Pfizer Inc, Collegeville, Pennsylvania, USA, 3 Global Clinical Pharmacology, Pfizer, Sandwich, UK Correspondence: Siv Jönsson, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24, Uppsala, Sweden. Tel.: +46 733 924 657, e-mail: siv.jonsson@farmbio.uu.se Number of references: 50 Number of figures: 4 Number of tables: 3 Key words: factor VIII, hemophilia, moroctocog alfa, NONMEM, population pharmacokinetics This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an ‘Accepted Article’, doi: 10.1002/cpt.716 This article is protected by copyright. All rights reserved.