Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/lam.13196 This article is protected by copyright. All rights reserved. PROF. MOAZUR RAHMAN (Orcid ID : 0000-0003-2892-1250) Article type : Original Article Restraining the multidrug efflux transporter STY4874 of Salmonella Typhi by reserpine and plant extracts Short running title: Inhibition of MDR pump STY4874 from Salmonella Typhi Anam Tariq a, b¶ , Maryam Sana a, b¶ , Aqsa Shaheen a, b, c¶ , Fouzia Ismat a, b , Sadia Mahboob a, b , Waqar Rauf a, b , Osman Mirza d , Mazhar Iqbal a, b , and Moazur Rahman a, b* a Drug Discovery and Structural Biology group, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan b Pakistan Institute of Engineering and Applied Sciences, P.O. Nilore, Islamabad, Pakistan c Department of Biochemistry and Biotechnology, University of Gujrat, Hafiz Hayat Campus, Gujrat, Pakistan d Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark ¶ These authors contributed equally to this work