ORIGINAL SCIENTIFIC REPORT Does Prior Percutaneous Endoscopic Gastrostomy Alter Post-operative Outcome After Esophagectomy Abu Bakar Hafeez Bhatti • Farrukh Hassan Rizvi • Anum Waheed • Syed Hassan Raza • Aamir Ali Syed • Shahid Khattak • M. Aasim Yusuf Ó Socie ´te ´ Internationale de Chirurgie 2014 Abstract Background With the introduction of neoadjuvant chemoradiotherapy in patients with esophageal carcinoma, nutritional access has become essential to counter deleterious effects of dysphagia. Current NCCN guidelines do not recommend PEG prior to esophagectomy in these patients, but there is little evidence for this recommendation. The objective of this study was to compare outcomes in patients who underwent esophagectomy with or without prior PEG placement. Methods We retrospectively reviewed 96 patients who underwent esophagectomy between 2005 and 2012 for esophageal carcinoma. Patients were divided into two groups; Group I (PEG ?ve) and Group II (PEG -ve). Patient characteristics, operative variables, and post-operative complications were compared. v 2 and Fisher’s test were used for categorical, while t test was used for interval variables. Results Median age was 51(18–70) years. Lower thoracic tumors were more common in Group I (69 vs. 63 %) (P = 0.04) and more patients underwent minimally invasive surgery in this group (50 vs. 2.6 %) (P \ 0.0001). Mean blood loss (326 vs. 465 ml) (P = 0.02) and ICU stay (1.6 vs. 4.3 days) (P = 0.01) were significantly lower in Group I. There was no 30-day mortality in Group I versus 10.5 % in Group II (P = 0.01). No significant difference in anastomotic leak and stricture rate was observed. Gastric conduit was used in all patients for reconstruction. One patient had malignancy in PEG site biopsy. Conclusion Percutaneous endoscopic gastrostomy before esophagectomy is safe and does not adversely impact post-operative outcomes. Introduction Neoadjuvant chemoradiotherapy before surgery for esophageal cancer has become the standard of care in locally advanced tumors. It increases margin negativity and overall survival with comparable complication rate [1]. Since patients with esophageal carcinoma usually present with dysphagia, nutritional depletion during the course of neoadjuvant treatment becomes a major concern. It has been shown that nutritional supplementation is beneficial in patients planned for future gastrointestinal surgery [2]. However, the best mode of enteral nutrition remains to be defined. Nutritional access can be achieved via feeding A. B. H. Bhatti (&) Á F. H. Rizvi Á S. H. Raza Á A. A. Syed Á S. Khattak Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan e-mail: abubakar.hafeez@yahoo.com A. B. H. Bhatti House No. A-391, Block-15, Gulistan-e-Jauhar, Karachi, Pakistan A. Waheed Sind Medical College, Karachi, Pakistan M. Aasim Yusuf Department of Gastroenterology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan 123 World J Surg DOI 10.1007/s00268-014-2812-8