Pak J Med Sci 2010 Vol. 26 No. 3 www.pjms.com.pk 733 Case Report SCREENING OF GASTRIC CANCER IN LIVER TRANSPLANTATION PATIENTS: A CASE REPORT AND REVIEW OF LITERATURE Abuzer Dirican 1 , Bulent Unal 2 , Nuray Bassulu 3 , Dincer Ozgor 4 , Cuneyt Kayaalp 5 , Sezai Yilmaz 6 ABSTRACT Liver and other solid organ transplant recipients are at an increased risk of developing several malignancies because of the immuno-suppressive treatment. Generally, patients who had a liver transplant have upper gastrointestinal tract complaints, which makes identification of gastric carcinoma symptoms in those patients difficult. A 58 years old liver transplant male patient presented to the hospital for his routine checkup and dyspeptic complaints. He had received a liver from a cadaver 18 months ago and his postoperative period had been uneventful. An esophagogastroduodenoscopy (EGD) revealed gastric cancer. A subtotal gastric resection with a D2 lymph node dissection was carried out. There was no recurrence during three years follow up. In order to make a timely identification of the occurrence of common malignancies such as gastric cancer, liver transplant recipients must be followed closely. KEY WORDS: Liver transplantation; Gastric cancer, Immunosuppression. Pak J Med Sci July - September 2010 Vol. 26 No. 3 733-735 How to cite this article: Dirican A, Unal B, Bassulu N, Ozgor D, Kayaalp C, Yilmaz S. Screening of gastric cancer in liver transplantation patients: A case report and review of literature. Pak J Med Sci 2010;26(3):733-735 1. Abuzer Dirican, Department of General Surgery 2. Bulent Unal, Department of General Surgery 3. Nuray Bassulu, Department of Pathology 4. Dincer Ozgor, Department of General Surgery 5. Cuneyt Kayaalp, Department of General Surgery 6. Sezai Yilmaz, Department of General Surgery 1-6: Inonu University School of Medicine, Malatya, Turkey Correspondence: Abuzer Dirican, M.D, Inonu University, Turgut Ozal Medical Center, Department of General Surgery, 44315 - Malatya, Turkey. E-mail: abuzerdirican@hotmail.com * Received for Publication: November 23, 2009 * Accepted: April 21, 2010 INTRODUCTION Liver and other solid organ transplant recipi- ents are at an increased risk of developing sev- eral malignancies because of the immune-sup- pressive treatment. 1 The overall incidence of malignancy for a transplant recipient has been estimated to be 20% in the 10-year follow-up period. 2 Lymphoproliferative, oropharyngeal, skin, colon, and renal malignant tumors were reported after liver transplantation. There is not enough data relevant to the incidence of gastric cancer after liver transplantation. In United States, 33 gastric cancers were identified among 7,000 malignancies reported to the Israel Penn Transplant Tumor Registry, and 3 of the 33 were observed after liver transplantation. 3 Here, we report a patient with gastric cancer who had a liver transplant for cirrhosis of the liver.