Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/crj.12924 This article is protected by copyright. All rights reserved. Safety of Exertional Desaturation in Idiopathic Pulmonary Fibrosis: An Electrocardiography Study Baruch Vainshelboim 1,2,3 , Genady Dobin 4 , Jonathan Myers 5 , Jose Oliveira 3 , Avraham Unterman 2,6 , Shimon Izhakian 2,6 and Mordechai Reuven Kramer 2,6 1. Master of Cancer Care Program, School of Health Sciences, Saint Francis University, Loretto, Pennsylvania, USA. 2. Pulmonary Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel. The institution where the study was conducted. 3. Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal. 4. Sports Medicine Center. Zinman College for Physical Education and Sports Sciences at the Wingate Institute, Israel. 5. Cardiology Division, Veterans Affairs Palo Alto Health Care System/ Stanford University, Palo Alto, California, USA. 6. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv; Israel. Corresponding Author: Baruch Vainshelboim, PhD, ACSM-RCEP, ACSM/ACS-CET. Master of Cancer Care Program, School of Health Sciences, Saint Francis University, Loretto, Pennsylvania, USA. Email: baruch.v1981@gmail.com Tel: 814-472-2704, Fax: 814-472-3140. Running Title: Safety of CPET in IPF Authors’ Contribution B.V. was responsible for study design and conception, data collection, results interpretation, statistical analysis, drafting, writing and submitting the manuscript. G.D. data collection and interpretation, drafting the article and revising it critically for important intellectual content. J.M. results interpretation, statistical analysis drafting the article and revising it critically for important intellectual content. J.O. study design and conception, results interpretation, statistical analysis drafting the article and revising it critically for important intellectual content. A.U. and S.I. participated in results interpretation, statistical analysis drafting the article and revising it critically for important intellectual content. M.R.K. principle investigator and supervisor physician of the study was responsible for designing the study and conception, results interpretation drafting the article and revising it critically for important intellectual content. All authors have read and approved the final version of the manuscript. None of the authors have conflict of interest No funding was received for this study