Research Article
Cutaneous Malignancy due to Arsenicosis in Bangladesh:
12-Year Study in Tertiary Level Hospital
Md. Iqbal Mahmud Choudhury ,
1
Nilufar Shabnam,
2
Tazin Ahsan,
3
S. M. Abu Ahsan,
4
Md. Saiful Kabir,
5
Rashed Md. Khan,
6
Md. Abdal Miah,
7
Mohd. Kamal Uddin,
8
and Md. Aminur Rashid Liton
9
1
Assistant Professor, Plastic Surgery Unit, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
2
Assistant Professor, Department of Surgery, BIRDEM Hospital and Ibrahim Medical College, Dhaka, Bangladesh
3
Honorary Medical Ofcer, Department of Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
4
Associate Professor and Head of the Department of Surgery, Ad-din Sakina Medical College, Jessore, Bangladesh
5
Professor and Head of Department of Dermatology and Venereology, National Medical College and Hospital, Dhaka, Bangladesh
6
Professor and Head of the Department of Dermatology & VD, Dhaka Medical College Hospital, Dhaka, Bangladesh
7
Assistant Professor, Department of Dermatology and Venereology, Centre for Medical Education, Dhaka, Bangladesh
8
Senior Consultant, Department of Dermatology, 250 bedded General Hospital, Gopalganj, Bangladesh
9
Assistant Professor, Department of Dermatology and Venereology, Holy Family Red Crescent Medical College and Hospital,
Dhaka, Bangladesh
Correspondence should be addressed to Md. Iqbal Mahmud Choudhury; drimcrony@gmail.com
Received 28 October 2018; Accepted 3 December 2018; Published 16 December 2018
Guest Editor: Sajib Chakraborty
Copyright © 2018 Md. Iqbal Mahmud Choudhury et al. Tis is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.
Bangladesh is grappling with the largest mass poisoning of a population in the world due to contamination of drinking water
with naturally occurring inorganic arsenic. It is estimated that 75 million people of 59 (out of 64) districts are at risk of drinking
contaminated water with arsenic above 50g/L. Long term exposure to arsenic causes cancers, including skin, lung, and bladder.
Tis is a randomized prospective study to see the prevalence of skin cancer from arsenic afected area of Bangladesh, as well as
their variation by geographical area, age, gender, location on the body, and socioeconomic conditions, in outpatient department
of plastic surgery unit of Bangabandhu Sheikh Mujib Medical University (BSMMU). A total of 960 patients with skin cancers
comprised of 528 males and 432 females were selected for the study from January 2004 to December 2015. In this 12-year study, we
found squamous cell carcinoma, basal cell carcinoma, melanoma, and Merkel cell carcinoma to be associated with the ingestion of
arsenic contaminated ground water. Tis is a refection of a small part of the total national scenario of devastating result of arsenic
mediated cancer in terms of skin malignancy. Tis study will help the future researchers who are contemplating to work on arsenic
induced health problem.
1. Introduction
Arsenic contamination of ground water in Bangladesh is
reported to be the worst problem in the world in terms
of afected population [1, 2]. Survey data from 2000 to
2010 have demonstrated that an estimated 35 to 77 million
Bangladeshi people, especially in rural area, have been chron-
ically exposed to arsenic through drinking water and daily
food [3–5]. Before 1970s, people in this country used surface
water for drinking and daily activities. Te surface water was
pathogen laden and as a result they sufered from several
types of diarrheal diseases in epidemic manner. To solve this
problem, since 1970s, the government and other international
organizations introduced shallow tube wells. Te people got
the apparent beneft but the hidden problem was discovered
years later. Te water from shallow tube wells (depth of 10-
70m) contains arsenic in toxic level, which causes a lot of
hazards to the human body. But ground water from deep
Hindawi
BioMed Research International
Volume 2018, Article ID 4678362, 9 pages
https://doi.org/10.1155/2018/4678362