_____________________________________________________________________________________________________ *Corresponding author: E-mail: drduweb@gmail.com; Ophthalmology Research: An International Journal 17(1): 1-7, 2022; Article no.OR.89552 ISSN: 2321-7227 Evaluation of Ocular Findings in Vitiligo Najat Belkheir a , Adam Albarghathi b , Ghait Alsdae c , Faraj Alshwin a and Gamal Duweb a* a Department of Dermatology, Faculty of Medicine, Benghazi University, Benghazi, Libya. b Department of Ophthalmology, Faculty of Medicine, Benghazi University, Benghazi, Libya. c Department of Dermatology, Faculty of Medicine, Sirte University, Sirte, Libya. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/OR/2022/v17i130245 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/89552 Received 10 May 2022 Accepted 15 July 2022 Published 19 July 2022 ABSTRACT Vitiligo is a pigmentary disorder of the skin and mucous membranes with worldwide incidence of 0.5-2%. The aim of this cross sectional study was to assess the ocular involvement in vitiligo patients. Two hundred patients clinically diagnosed vitiligo attending vitiligo clinic, dermatology department, Jomhorya hospital, Benghazi-Libya over a period of 6 months enrolled in this cross- sectional study. All patients were exposed to detailed disease history and thorough dermatological examination. Out of the total cases, 100 patients had a standard Ophthalmologic examination in cooperation with an ophthalmologist in Benghazi eye hospital. Results of our study showed a slightly higher prevalence of vitiligo in females (male: female ratio 1:2.8). The mean age of onset for males was 22.4 years and for females 24.8 years and 58.5% of patients develop vitiligo below 20 years of age. Generalized vitiligo was the commonest clinical type of vitiligo (57.5%). The relationship between the duration of the disease and its type was statistically significant (P<0.05), there was also a significant relationship between the type of vitiligo and its severity (P< 0.01). Sixteen patients (8%) had segmental vitiligo and the face was the common site involved. The lower limbs were the most commonly affected sites of the body (57%). Ocular changes were seen in 40% of patients and specific ocular abnormalities like uveitis, iritis, and iris and retinal pigmentary abnormalities are present in 15% of patients, nonspecific ocular abnormalities were present in 33% of patients. There was no statistically significant correlation between specific ocular abnormalities, severity and duration of vitiligo. Original Research Article