Saza Fitria, Ede Surya Darmawan, and Amelia Rizki Alfriantin Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 10 No. 1 (2022) 93-102 doi: 10.20473/jpk.V10.I1.2022.93-102 93 ©2022. Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education. Open Access under CC BY-NC-SA License. Received: 31-08-2021, Accepted: 01-03-2022, Published Online: 23-03-2022 Faktor Risiko Penularan Virus SARS-Cov 2 pada Tenaga Kesehatan Risk Factors for Transmission of the SARS-Cov 2 Virus in Health Workers Saza Fitria 1) , Ede Surya Darmawan 1) , Amelia Rizki Alfriantin 1) 1 Faculty of Public Health, Universitas Indonesia, Jakarta, Indonesia Email: dr.saza89@gmail.com ABSTRACT Background: Healthcare workers (HCWs) serve as front liners in the battle against COVID- 19. They are often expected to be in constant contact with infected patients, posing higher risk of transmission. To date, literature on risk factors of COVID-19 transmission in HCWs are still limited. Purpose: We conducted this systematic review to identify the risk factors for SARS-CoV-2 virus transmission among HCWs. Methods: We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol. Four internet databases were searched using predefined search terms. The keywords used were {“COVID-19” OR “SARS-CoV-2”}, {“transmission” OR “transmission risk”}, and (“healthcare professionals” OR “healthcare workers” OR “healthcare staff” ). All English articles which were published from January 2020 to June 2021 involving HCWs in hospitals treating COVID-19 were included into the study. Results: Out of initial 636 studies found using the predefined search terms, 18 studies fulfilled the inclusion criteria and were subsequently analyzed. We found that risk factors for COVID-19 could be divided into 5 categories: use of personal protective equipment (PPE), infection control procedures, unsafe workplace practices, provision of institutional support, and presence of individual risk factors in healthcare workers. Good hospital governance is necessary to establish policies regarding control of COVID-19 infection which will protect the patients and HCWs. Conclusion: Proper use of PPE, compliance to proper infection control procedures, establishment of safe workplace practices, provision of institutional support for prevention measures, and lack of individual risk factors may reduce the transmission risk of SARS-CoV- 2 virus among healthcare workers. Further studies are warranted to identify methods for reducing incidence and mortality rate due to COVID-19 at HCWs. Keyword: COVID-19, healthcare workers, risk factors, transmission INTRODUCTION Coronavirus Disease 2019, abbreviated as COVID-19, started with a series of clusters of pneumonia-like symptoms in December 2019 in China (Xiao et al., 2020). The disease has rapidly evolved into a pandemic encompassing the entire world (Bandyopadhyay et al., 2020). As of June 2021, the number of confirmed cases reported globally now exceeds 175 million, with 3 million confirmed deaths (The World Health Organization, 2021). Healthcare workers (HCWs), including doctors, nurses, laboratory technicians, physiotherapists, and many others are responsible for the treatment and patient care (Xiao et al., 2020). In their line of work, HCWs were expected to be constantly in close contact with patients, including patients confirmed as having COVID-19, posing for them higher risks for transmission than normal populations. One previous study reported a mortality rate of 37.2 deaths per 100 infections for HCWs, especially those belonging to the elderly age group. As of May 2020, a total of 152.888 HCWs have been infected with COVID-19, accounting for 3.9% of the population worldwide. Among these, 1413 HCWs were reported dead due to COVID-19, making up 0.5% of the number of deaths worldwide (Bandyopadhyay et al., 2020). Previous study also reported that at least 90,000 healthcare workers worldwide have been infected by COVID-19. The study showed a rate of 5.62% (273 out of 4854 cases) infection among HCW in Iran (Sabetian et al., 2021). Healthcare workers working on the front lines in the battle against COVID-19 face challenges in providing treatment for their