ORIGINAL SCIENTIFIC REPORT Robot-Assisted Transaxillary Thyroidectomy (RATT): A Series Appraisal of More than 250 Cases from Europe Gabriele Materazzi 1 • Lorenzo Fregoli 1 • Piermarco Papini 1 • Sohail Bakkar 1 • Malince Chicas Vasquez 1 • Paolo Miccoli 1 Ó Socie ´te ´ Internationale de Chirurgie 2017 Abstract Background Robot-assisted transaxillary thyroidectomy (RATT) is widely accepted in Asian countries. However, concerns regarding the balance between its real advantages and safety and cost have been raised by North American authorities. In Europe, assessments have been limited by small numbers since now. The purpose here is to report a large European experience with RATT. Methods A retrospective analysis was conducted of 257 patients who underwent RATT for nodular disease between February 2012 and September 2016. Data collected included patient demographics, diagnosis, ultrasound-estimated mean thyroid volume and nodule size, type of resection, operative time, postoperative pain and morbidity, and the hospital length of stay. Pain was assessed by visual analog scale score 12 h postoperatively (on the first postoperative day, before discharge). Feasibility, effectiveness, and safety were the outcomes of interest. Follow-up of thyroid carcinoma patients was carried out measuring thyroglobulin levels and ultrasound examination (median follow-up 24 months (6–48 months)). First control after 12 months and successively once a year. Results There were 253 women and 4 men, with a mean age of 37.3 years. Indications included benign disease in 116, papillary carcinoma in 56, and indeterminate nodule in 85. Mean thyroid volume was 16.8 mL, and nodule size was 25.3 mm. A hemithyroidectomy was performed in 138 patients and total thyroidectomy in 118. The mean operative time was 77.5 min for the former and 99.7 min for the latter. One conversion was required. Complications included transient hypoparathyroidism in 7/118 (total thyroidectomy) patients (5.9%), transient vocal fold palsy in 3/257 (1.1%), 1 delayed tracheal injury (0.4%), and 3 postoperative hematoma (1.1%). Mean visual analog scale score was 1.79, and the mean length of stay was 1.6 days for hemithyroidectomy and 1.9 days for total thyroidectomy. Conclusion RATT is safe and effective and could serve as a viable treatment modality in selected cases. Introduction The concept of minimal access and cosmetic thyroid sur- gery is an appealing one because a large proportion of patients are young women who may be equally concerned with therapeutic and cosmetic outcomes. Among the mul- tiple minimally invasive endoscopic and cosmetic proce- dures described in recent years [1–5] is robot-assisted transaxillary thyroidectomy (RATT), which was first introduced in South Korea in 2009 [6]. RATT is considered an appealing option not only to patients for whom it offers a thyroidectomy free of a neck scar, but also to surgeons for whom it offers improved ergonomics and dexterity compared with its videoscopic equivalents. Although RATT has become a widely accepted and used treatment & Gabriele Materazzi gmaterazzi@yahoo.com 1 Department of Surgical Pathology, Medical, Molecular and Critical Area, University of Pisa, Via Paradisa 2, Pisa, Italy 123 World J Surg DOI 10.1007/s00268-017-4213-2