*Correspondence: drsapna_chauhan@yahoo.com (Received: January 14, 2021; accepted: May 14, 2021) Citaton: Chauhan S, Surender. Clinico-Mycological Profle of Otomycosis in Chronic Suppuratve Otts Media Patents Atending a Tertary Care Teaching Hospital. J Pure Appl Microbiol. 2021;15(2):813-818. doi: 10.22207/JPAM.15.2.35 © The Author(s) 2021. Open Access. This artcle is distributed under the terms of the Creatve Commons Atributon 4.0 Internatonal License which permits unrestricted use, sharing, distributon, and reproducton in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creatve Commons license, and indicate if changes were made. Chauhan & Surender | J Pure Appl Microbiol | 15(2):813-818 | June 2021 Artcle 6856| htps://doi.org/10.22207/JPAM.15.2.35 Print ISSN: 0973-7510; E-ISSN: 2581-690X ReseARCh ARtiCle OPeN ACCess www.microbiologyjournal.org 813 Journal of Pure and Applied Microbiology Clinico-Mycological Profle of Otomycosis in Chronic Suppuratve Otts Media Patents Atending a Tertary Care Teaching Hospital Sapna Chauhan 1 * and surender 2  1 Department of Microbiology, Muzafarnagar Medical College, Muzafarnagar - 251 203, Utar Pradesh, India. 2 Department of Anaesthesia, Muzafarnagar Medical College, Muzafarnagar - 251 203, Utar Pradesh, India. Abstract Chronic Suppuratve Otts Media (CSOM) is commonly encountered chronic infammaton of middle ear as well as the mastoid cavity due to dysfuncton of Eustachian tube followed by microbial infecton. Fungal infecton in CSOM is now a major otolarynological problem in India not only in children but in adults too. Excessive use of steroids, antbiotcs, cytotoxic chemotherapies and immunosuppressive diseases has increased the incidence of otomycosis in recent years. To defne the aetology of clinically diagnosed otomycosis. To isolate and identfy fungal agents and their associaton with diferent factors (age, sex, predisposing factors). A total of 100 clinically diagnosed patents of CSOM with suspicion of otomycosis were included in the study. Patents where passing swab is difcult as with canal stenosis were excluded. Samples were taken using sterile swabs and studied for microbial profle. Male to female rato in study was 1.6:1. The most common fungi isolated in CSOM cases was Aspergillus fumigatus followed by Aspergillus niger. Other fungus isolated were Aspergillus favus, Penicillium species, Mucor species and Candida species. 04 samples showed mixed growth of Aspergillus species and Candida species. In our study we concluded that Aspergillus complex was most commonly isolated fungi in CSOM cases. Keywords: CSOM, Otomycosis, Aspergillus spp