Accepted Manuscript Defective TLR9-driven STAT3 activation in B cells of patients with CVID Arturo Borzutzky, Ingrid Rauter, Ari Fried, Rima Rachid, Douglas R. McDonald, Lennart Hammarstrom, Bodo Grimbacher, Roshini S. Abraham, Raif S. Geha PII: S1521-6616(18)30498-4 DOI: doi:10.1016/j.clim.2018.08.008 Reference: YCLIM 8089 To appear in: Clinical Immunology Received date: 17 August 2018 Accepted date: 17 August 2018 Please cite this article as: Arturo Borzutzky, Ingrid Rauter, Ari Fried, Rima Rachid, Douglas R. McDonald, Lennart Hammarstrom, Bodo Grimbacher, Roshini S. Abraham, Raif S. Geha , Defective TLR9-driven STAT3 activation in B cells of patients with CVID. Yclim (2018), doi:10.1016/j.clim.2018.08.008 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.