2018
Vol.4 No.1:2
Commentary
DOI: 10.21767/2471-805X.100035
iMedPub Journals
www.imedpub.com
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© Under License of Creative Commons Attribution 3.0 License | This article is available in: http://pediatrics.imedpub.com/archive.php
Journal of Pediatric Care
ISSN 2471-805X
Abstract
Congenital diaphragmatc hernia is a conditon characterized by a defect in the
diaphragm that leads to the protrusion of the abdominal contents in the thoracic
cavity which interferes in the pulmonary development. Diaphragmatc eventraton
is a very infrequent conditon in children, asymptomatc or commonly present with
low or gastrointestnal respiratory manifestatons and whose diagnosis is based
on an incidental fnding when requestng images to verify a diagnostc suspicion
occurring in most cases of late occurrence. It can be of congenital or acquired
cause. The prognosis in general is good, with probable complicatons being chronic
lung infecton, diaphragmatc rupture, ulcers and stomach volvulus. Treatment is
a topic depend size and locaton of the defect, size and locaton of the defect,
some pediatric surgeons do not operate if the patent is asymptomatc and only
plicate the symptomatc patents. Due to its importance in pediatric populaton,
through this is intended to make a quick review of the updated literature on the
subject contributng to have relevant informaton regarding the issue cooperatng
with the diagnosis and appropriate treatment in our practce.
Keywords: Congenital Diaphragmatc Hernia (CDH); Diaphragmatc eventraton;
Diaphragmatc hernia; Congenital anomalies
Pediatric Congenital Diaphragmatc Hernia
Received: November 22, 2017; Accepted: April 10, 2018; Published: April 13,
2018
Irina Suley Tirado Pérez
1*
,
Ulfran De Jesús Castro Salas
2
and Andrea Carolina Zarate
Vergara ACZ
3
1 Master Pediatric Palliatve Care,
Pediatric Intensive Care Student,
University of Santander, Colombia
2 Pediatric Teacher, University of
Santander, Colombia
3 Pediatric Intensive Care Student,
University of Santander, Colombia
Corresponding author:
Irina Suley Tirado Pérez
irinasuley@gmail.com
Magister Pediatric Palliatve Care, Center
for Research and Teaching, Graduate
Student of Pediatric Intensive Care Level I,
University of Santander, Columbia.
Tel: 3145598697
Citation: Pérez IST, Salas UDJC, Vergara ACZ
(2018) Pediatric Congenital Diaphragmatc
Hernia. J Pedfafr Care. Vof.4 No.1:2
Introducton
Congenital diaphragmatc hernia (CDH) is a defect that occurs
in 1 in 3,000 live births, of which approximately 60% occur in
isolaton without other congenital anomalies. This is a rare
congenital anomaly of the diaphragm that occurs due to poor
embryogenesis with atrophy of the diaphragm muscle fbers
and loss of muscle tone. It is more frequent on the lef side,
and bilateral cases have been reported, male predominance
is also recognized. It is associated with gestaton infectons
such as rubella and cytomegalovirus, Jarcho-Levin's spóndyl-
thoracic dysplasia, malformatons such as pulmonary hypoplasia,
pulmonary sequestraton, congenital heart disease, renal ectopia,
gastric volvulus, chromosomal diseases, various myopathies and
spinal cord abnormalites. Ofen the diagnosis of diaphragmatc
eventraton is a fnding when performing chest X-rays in a
respiratory distress syndrome or in febrile conditons. Considering
that many patents are asymptomatc but at the same tme with
bronchial segmentaton and alveolar multplicaton extending
up to 8 years of age and that the partal occupaton of the
hemithorax is directly detrimental to the complete development
of that lung, raises the discussion about the indicaton and
tming of the surgical correcton of this pathology. The most
frequent defect occurs in the lef posterolateral region of the
diaphragm (Bodahlek hernia), but may be right in 15% of cases or
bilateral in about 1-2%. Complete agenesis of the diaphragm and
eventraton are very rare manifestatons. The prenatal diagnosis
of CDH is has been increased thanks to prenatal ultrasound
screening programs, from being a diagnosis of neonatal urgency
to an increasingly well-known conditon since the fetal stage.
Immediate treatment at birth includes bowel decompression,
avoidance of mechanical ventlaton to the extent possible.
The main management focus includes non-invasive ventlaton,
hemodynamic monitoring and treatment of pulmonary
hypertension followed by surgery. Although inhaled nitric oxide
is not approved by the FDA for the treatment of CDH-induced
pulmonary hypertension, it is commonly used. Extracorporeal
membrane oxygenaton (ECMO) is typically considered afer
the failure of conventonal medical treatment for neonates with
gestatonal age ≥ 34 weeks or weighing >2 kg with CDH that do
not have large associated lethal abnormalites. Multple factors