Experimental and Theoretical Study of the Living Polymerization of N-Silylphosphoranimines. Synthesis of New Block Copolyphosphazenes Silvia Sua ́ rez Sua ́ rez, David Presa Soto, Gabino A. Carriedo,* , Alejandro Presa Soto,* , and Anne Staubitz* , Department of Organic and Inorganic Chemistry, IUQOEM, University of Oviedo, Julia ́ n Clavería, 33006 Oviedo, Spain Otto-Diels-Institute for Organic Chemistry, University of Kiel, Otto-Hahn-Platz 3/4, 24118 Kiel, Germany * S Supporting Information ABSTRACT: The sequential living polymerization of N-silylphosphoranimines for the synthesis of polyphosphazene-b-polyphosphazene diblock copolymers (PP-b-PP) has been studied both experimentally and theoretically. For the experiments, BrMe 2 PN-SiMe 3 , [Cl 3 PNPCl 3 ][X] (X = PCl 6 - , Cl - ), Cl 3 PN-SiMe 3 , ClMe 2 PN-SiMe 3 , and [Me 3 PNPMe 2 Cl] + were used as representative model reagents. Density functional theory (DFT) calculations in the gas phase adjusted for solvent effects on ClMe 2 PN- SiMe 3 , [Cl 3 PNPCl 3 ] + , Cl 3 PN-SiMe 3 , and ClMe 2 PN-SiMe 3 confirmed the experimental observations. The results have shown the necessity of starting with mono- end-capped initiators to avoid the formation of triblock chains. It was also demonstrated that the nature of the nucleophilic N-silylphosphoranimines and the electrophilic cationic end groups of the living polyphosphazenes strongly affects the polymerization reaction, imposing limits to its synthetic potential. Thus, good electron donor N-silylphosphor- animines, i.e. XR 2 PN-SiMe 3 , react better with electron-deficient cationic end groups such as N-PCl 3 + , probably by molecular orbital (MO) control. The results led to the designed synthesis of well-defined PP-b-PP block copolymers with narrow molecular weight distributions of formula [N P(Ph)(Me)] n -b-[NP(OCH 2 CF 3 ) 2 ] m and [NP(Ph)(Me)] n -b-[NP(O 2 C 12 H 8 )] m , which are excellent candidates for micellation studies. INTRODUCTION The presence of elements other than carbon in polymeric chains (inorganic polymers) can generate interesting and useful properties such as flexibility at low temperatures, thermal, radiative, and oxidative stability, flame retardancy, new electrical and optical features, and novel chemical reactivity. 1a,b Since the early studies of F. Gordon A. Stone in this area, 1c-e the synthesis of those materials remains an important challenge. Within the large variety of monomeric precursors containing main-group elements in the structure, the phosphoranimines R 3 PNR, discovered in 1919 by Staudinger and Meyer, 2 have contributed to significant advances in this field. The chemistry of these molecules has been the subject of intense study. 3 Phosphoranimines undergo a variety of reactions such as 1,2- additions, 4 cyclodimerizations, 5 aza-Wittig, 6 and catalytic meta- thesis 7 and have been used as ligands in main-group 8 and transition-metal chemistry. 9 Moreover, they are important monomeric precursors for a large variety of polyphosphazenes, [NPX 2 ] n , a class of inorganic polymers consisting of alternating phosphorus and nitrogen atoms in the backbone. The first known example, [N PCl 2 ] n (poly- (dichlorophosphazene)), was prepared in the late 1890s as a cross-linked, hydrolytically unstable elastomer. 10 Since then, various synthetic methods to obtain non-cross-linked [N PCl 2 ] n (1) have been achieved, on the basis of the ring-opening polymerization (ROP) of hexachlorocyclotriphosphazene [N PCl 2 ] 3 (2), either at ca. 200-250 °C (Chart 1, eq 1) 11 or at room temperature in the presence of trialkylsilyl carboranes as initiators. 12 Non-cross-linked [NPCl 2 ] n (1) proved to be an essential intermediate to synthesize numerous polyphospha- zene derivatives [NPX 2 ] n , by macromolecular substitution of the chlorine atoms by oxygen or nitrogen donor nucleophiles (X). 13 However, some polyphosphazenes, mainly those bearing alkyl or aryl substituents, are inaccessible by these strategies, because treatment of [NPCl 2 ] n (1) with aryl or alkyl Grignard or lithium reagents leads to decomposition of the polymers. Another route to access this pivotal polymer is the use of phosphoranimines. Thus, heating (N-phosphoryl)- trichlorophosphoranimine Cl 3 PNP(O)Cl 2 affords [N PCl 2 ] n (1) at ca. 250 °C by condensation polymerization which proceeds with elimination of P(O)Cl 3 (Chart 1, eq 2). 14 Furthermore, the introduction of phosphoranimines as monomers allowed the successful preparation of poly(alkyl/ Special Issue: F. Gordon A. Stone Commemorative Issue Received: October 20, 2011 Published: January 24, 2012 Article pubs.acs.org/Organometallics © 2012 American Chemical Society 2571 dx.doi.org/10.1021/om201012g | Organometallics 2012, 31, 2571-2581